Uremia increases glomerular size, but not cortical collagen content in LDLr-/- mice.

<p>Representative pictures of kidney sections from control (SHAM), uremic (NX) and liraglutide treated uremic (NX LIRA) mice stained with Massons trichrome (<b>A</b>). Scale bar = 200 μm for top row and 100 μm for bottom row. Glomerular diameters were measured (<b>B</b>) (25–49 glomeruli were assessed per kidney, n = 7–8 in each group) and collagen deposition in the kidney cortex was quantified (<b>C</b>) (n = 5–7 in each group) using the Visiopharm software. **p<0.01, as determined by 1-way ANOVA followed by Sidak’s multiple comparisons post-test.