T cell specific HK2 deletion is dispensable for T cell development.

<p>Thymus and spleens from 5–6 week old naïve WT and HK2 KO animals were isolated. (A) Representative FACS plots and bar graph showing the frequency and number of total thymocytes, CD4+ CD8- T cells, CD4- CD8+ T cells, CD4+CD8+ T cells and CD4+CD8- Foxp3+ Treg cells in Thymus. (B) Representative FACS plot showing the TCR-beta expression gated on CD8+ CD4- T cells in the thymus. (C) Representative FACS plots and histogram showing the frequency and number of CD4+ CD8- T cells, CD4- CD8+ T cells and CD4+CD8- Foxp3+ Treg cells in Spleen. Gated on live cells. Data represents the mean ± SEM of more than 2 independent experiments (n = 3 mice/group). P≤0.001(*).