HK2 deletion in T cells had minimal effects on HSV-1 specific CD8 T cells and expression of CD44 and CD62L on CD4 T cells.

<p>(A) WT and HK2 KO animals were ocularly infected with HSV-1 and day 15pi draining cervical lymph nodes were isolated. Representative FACS plots and bar graphs showing the frequency and number of activated (CD44+CD62L-), naïve (CD44-CD62L+) and memory CD4 T cells (CD44+CD62L+). Data represents means ± SEM from three independent experiments (n = 3/group). (B) WT and HK2 KO animals were infected in their footpad with HSV-1 KOS and at day 4pi popliteal lymph nodes were isolated. Representative FACS plots and bar graph indicates the frequency and number of CD8 T cells expressing IFN-gamma upon stimulation with gB peptide. Data represents means ± SEM from two independent experiments (n = 3/group).