Tissue distribution of HSV-2 specific memory T cells following genital HSV-2 infection of guinea pigs.

<p>Hartley guinea pigs were infected ivag with HSV-2 strain MS and lymphocytes isolated from the indicated tissues on days 99-150 post infection. HSV-specific, IFN-γ SCs were detected and quantified by IFN-γ ELISPOT. The frequency of HSV-specific, IFN-γ SC per 10⁶ cells is given in <b>A,C,E,G</b> and the total number of HSV-specific, IFN-γ SC is given in <b>B,D,F,H</b> for each tissue. Each data point represents results from an individual animal. (* <i>P</i><0.05; ** <i>P</i><0.01, Student's <i>t</i> test; *** <i>P</i><0.0001, Chi square).