Decreased recruitment of NK, CD4+ and CD8+ T cells in HSV-2 infected Fas and FasL-deficient mice.

<p>Vaginal tissue samples from Fas <i>(−/−)</i>, FasL <i>(−/−)</i> and WT (C57BL/6) mice (n = 5 mice per strain) isolated at 3 and 7 day of HSV-2 infection were pooled and used to prepare single cell suspensions and further analyzed for the total numbers of CD4+ T cells (A), CD8+ T cells (B) and NK cells (C). Uninfected mice were used as controls. Each bar represents the mean total cell numbers from 5 separate experiments (N = 5) ± SEM. * represent significant differences with <i>p</i>≤0.05, **<i>p</i>≤0.01.