FORMULASI GEL ANTIOKSIDAN EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L) dengan BASIS CARBOPOL

The skin of the mangosteen fruit (Garcinia mangostana L.) contains xanthones which is a powerful antioxidant. Antioxidants are substances that neutralize free radicals that can protect the body from the biological system adverse effects arising from the process or reaction that causes excessive oxidation. The purpose of this study is to formulate extract of mangosteen rind with a particular concentration in the form of gel formulation of antioxidants and determine physical and chemical properties.\ud The research is experimental research. Object studied is mangosteen rind extract (Garcinia mangostana L.) were extracted using maceration. Formula made with mevariasikan 3 concentration of the ethanol extract of mangosteen rind 0.2%, 0.4%, and 0.6% use a gelling agent carbopol 940 0.5%. Tests carried out on organoleptic gel formulation (odor, color, texture), homogeneity, pH, skin irritation, and the gel dispersive power of antioxidants.\ud Results of testing physical properties, gel ethanol extract of mangosteen rind using a base of carbopol 940 in formula I with a concentration of 0.2% extract of yellow vaginal discharge, formula II with a 0.4% concentration of yellow-brown, formula III with a concentration of 0.6% yellow brown and smelled each formula oleum citri and smooth creamy texture, has a pH value of 6 with good homogeneity and does not irritate. Dispersive power generated at each antioxidant gel formula has a value that does not meet the requirements of the spread. \ud From this study it can be concluded that the ethanol extract of the skin of the mangosteen fruit (Garcinia mangostana L.) can be formulated as a gel antioxidants. The best antioxidant gel formula is the formula I with a 0.2% concentration of the extracts from the results of testing physical properties are quite stable and has a color more transparent.\u