A. Z projections of experimental (confocal) and simulated microvascular networks grown in low, medium, or high anisotropy collagen. Depth of field = 200 μm. B. XY-plane ODFs for each experimental or simulated case. Overlap is seen between the confocal and EFD field ODFs for all cases. The presented results are for 4 mg/mL collagen. (TIF)</p
<p>Representative fluorescent images of a confluent EC layer on the surface of collagen gel (<b>A</b...
A fundamental understanding of the mechanical properties of the extracellular matrix (ECM) is critic...
Selected strains of vascular endothelial cells, grown as confluent monolayers on tissue culture plas...
A. Z projections of experimental (confocal) and simulated microvascular networks grown in low, mediu...
Z projections of microvascular networks grown in low (left) and high (right) anisotropy collagen usi...
A-C. Top-down view of the initial fibril directions for each element. Directions were randomly sampl...
<p>Increasing the density of the ECM reduced neovascularization in both the experiments and computat...
Sensitivity study–Collagen fibril orientation weight (α). Top: Low-density collagen results for simu...
Alignment of collagen type I fibers is a hallmark of both physiological and pathological tissue remo...
As the interaction between tissue adaptation and the mechanical condition within tissues is complex,...
The collagen architecture is the major determinant of the function and mechanical behavior of cardio...
The collagen architecture is the major determinant of the function and mechanical behavior of cardio...
<p>(A) Schematic drawing of the polycarbonate frame, (B) low (size: 25×5×1 mm) and (C) high (size: 2...
Simulations were performed with microvessels seeded on the proximal (left) end of a rectilinear doma...
Background Mechanical characteristics of vascular tissue may play a role in different arterial patho...
<p>Representative fluorescent images of a confluent EC layer on the surface of collagen gel (<b>A</b...
A fundamental understanding of the mechanical properties of the extracellular matrix (ECM) is critic...
Selected strains of vascular endothelial cells, grown as confluent monolayers on tissue culture plas...
A. Z projections of experimental (confocal) and simulated microvascular networks grown in low, mediu...
Z projections of microvascular networks grown in low (left) and high (right) anisotropy collagen usi...
A-C. Top-down view of the initial fibril directions for each element. Directions were randomly sampl...
<p>Increasing the density of the ECM reduced neovascularization in both the experiments and computat...
Sensitivity study–Collagen fibril orientation weight (α). Top: Low-density collagen results for simu...
Alignment of collagen type I fibers is a hallmark of both physiological and pathological tissue remo...
As the interaction between tissue adaptation and the mechanical condition within tissues is complex,...
The collagen architecture is the major determinant of the function and mechanical behavior of cardio...
The collagen architecture is the major determinant of the function and mechanical behavior of cardio...
<p>(A) Schematic drawing of the polycarbonate frame, (B) low (size: 25×5×1 mm) and (C) high (size: 2...
Simulations were performed with microvessels seeded on the proximal (left) end of a rectilinear doma...
Background Mechanical characteristics of vascular tissue may play a role in different arterial patho...
<p>Representative fluorescent images of a confluent EC layer on the surface of collagen gel (<b>A</b...
A fundamental understanding of the mechanical properties of the extracellular matrix (ECM) is critic...
Selected strains of vascular endothelial cells, grown as confluent monolayers on tissue culture plas...