Assessment of biological activity of natural iron-containing mineral waters at their internal application

Babov K. D., Gushcha S. G., Voloshenyuk I. O., Nasibullin B. A., Badiuk N. S., Zabolotna I. B. Assessment of biological activity of natural iron-containing mineral waters at their internal application. Journal of Education, Health and Sport. 2020;10(6):364-372. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2020.10.06.038 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.06.038 https://zenodo.org/record/3936063 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2020; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 29.05.2020. Revised: 02.06.2020. Accepted: 30.06.2020. Assessment of biological activity of natural iron-containing mineral waters at their internal application K. D. Babov1, S. G. Gushcha1, I. O. Voloshenyuk2, B. A. Nasibullin1, N. S. Badiuk3, I. B. Zabolotna1 1State Institution «Ukrainian Research Institute of Medical Rehabilitation and Balneology of the Ministry of Health of Ukraine», Odessa, Ukraine 2Vlado Medychnyy Tsentr «Try Syny ta Don'ka» Hotel Complex, Skhodnitsa, Lvil region, Ukraine 3Ukrainian Research Institute of Transport Medicine of the Ministry of Health of Ukraine Abstract In experiments on rats of the Wi-star line, the influence of two iron-containing weakly mineralized mineral waters with a high content of organic matter (MW) from the sources № 13 and № 15 of Skhidnytsia deposit (Ukraine). It was determined that both MW do not have a toxic effect on their use on animals, as evidenced by the lack of significant structural and functional changes in the tissues of the stomach, kidneys, liver, and heart. It is established that MW from source No. 13 changes the activity of transamination processes in hepatocytes, increases bile formation and biliary excretion, and activates red blood counts. MW from source No. 15 has a similar effect, but more significantly affects the metabolism, red blood, and immune system. The research results justify the use of these iron-containing MW for the correction of iron deficiency conditions in laboratory animals. Keywords: ferrous mineral waters; metabolism; red blood; structural changes of internal organ