Major changes New command assembleContigs for assembling longest possible contig TCR/IG receptor sequences from several intersecting sequences containing clonal sequence. E.g. assemble all possible sequence information outside CDR3. New command analyze for running optimized mixcr pipelines with one single command. Two pipelines which cover most practical cases are implemented analyze amplicon and analyze shotgun. New file format .clna for storing clones with alignments including alignments clones mapping Complete refactoring of command line interface New option --resume for resuming aborted / partially completed execution Implemented -nFeatureImputed and -aaFeatureImputed to export gene feature sequences imputing unavailable regions from ...
Chain distribution is back in report file V/J chimera detection and elimination mechanism; new param...
Additional fix for error in exportAlignments / exportClones with repeated non-parametrized options A...
Major changes (beta) Added JSON-formatted reports. Use --json-report option in align, extendAlignme...
Major changes Fixes clone oversplitting in assembleContigs in noizy (e.g. single-cell) data with su...
Major review of all analysis steps for non-enriched libraries (RNA-Seq, etc...). Efficiency of TCR/I...
Major fix for analyze action (wrong aligner paramters were used before) Also several minor fixes to ...
Fixes NPE in very rare cases with incompatible V gene selection for assembleContigs in case of parti...
Major changes Alignments are forced to the corresponding edge if the same V/J gene is detected in t...
Comprehensive support for Single-Cell and Molecular barcodes flexible and fast pattern matching eng...
Fixes rare inconsistency in behaviour between paired-end and single-end aligners, clone assembler an...
Major changes Additional check for the same V hits in merging sequences in assemblePartial Fix: lis...
This fixes problem with repeated CLI options in export VRegionWithP now is used as featureToAlign fo...
Fixed bug with wrong V gene selection in assembleContigs. analyze doesn't use .clna when contig asse...
Minimal thresholds added for V and J alignments in extendAlignments minimalNOverlap in assembleParti...
Overview MiXCR 4.1 features two major functional upgrades: essential fixes and improvements for the...
Chain distribution is back in report file V/J chimera detection and elimination mechanism; new param...
Additional fix for error in exportAlignments / exportClones with repeated non-parametrized options A...
Major changes (beta) Added JSON-formatted reports. Use --json-report option in align, extendAlignme...
Major changes Fixes clone oversplitting in assembleContigs in noizy (e.g. single-cell) data with su...
Major review of all analysis steps for non-enriched libraries (RNA-Seq, etc...). Efficiency of TCR/I...
Major fix for analyze action (wrong aligner paramters were used before) Also several minor fixes to ...
Fixes NPE in very rare cases with incompatible V gene selection for assembleContigs in case of parti...
Major changes Alignments are forced to the corresponding edge if the same V/J gene is detected in t...
Comprehensive support for Single-Cell and Molecular barcodes flexible and fast pattern matching eng...
Fixes rare inconsistency in behaviour between paired-end and single-end aligners, clone assembler an...
Major changes Additional check for the same V hits in merging sequences in assemblePartial Fix: lis...
This fixes problem with repeated CLI options in export VRegionWithP now is used as featureToAlign fo...
Fixed bug with wrong V gene selection in assembleContigs. analyze doesn't use .clna when contig asse...
Minimal thresholds added for V and J alignments in extendAlignments minimalNOverlap in assembleParti...
Overview MiXCR 4.1 features two major functional upgrades: essential fixes and improvements for the...
Chain distribution is back in report file V/J chimera detection and elimination mechanism; new param...
Additional fix for error in exportAlignments / exportClones with repeated non-parametrized options A...
Major changes (beta) Added JSON-formatted reports. Use --json-report option in align, extendAlignme...