Major changes Alignments are forced to the corresponding edge if the same V/J gene is detected in the opposite PE read mate Average quality threshold (-OaverageQualityThreshold=...) in assembleContigs increased to 20 Added exportAlignmentsForClones action All indels in homopolimeric stretches are now shifted left in all alignment algorihtms Smarter base V/J/C hit selection in assembleContigs Read quality trimming (see help for --trimming-window-size and --trimming-quality-threshold options in align) (disabled by default until 3.1) Fix exception in -mutationsDetailed and similar export options Fixes in step skipping logic in analyze (additional automatic parameter adjustment for VDJC libraries covering only VRegion) Several more fixes for a...
Major review of all analysis steps for non-enriched libraries (RNA-Seq, etc...). Efficiency of TCR/I...
Fixes V/J/C oversplitting issue in noizy data Additional fix for empty block exception in assemble a...
This fixes problem with repeated CLI options in export VRegionWithP now is used as featureToAlign fo...
Major changes Additional check for the same V hits in merging sequences in assemblePartial Fix: lis...
Major changes Fixes clone oversplitting in assembleContigs in noizy (e.g. single-cell) data with su...
Fixes NPE in very rare cases with incompatible V gene selection for assembleContigs in case of parti...
Major fix for analyze action (wrong aligner paramters were used before) Also several minor fixes to ...
Minimal thresholds added for V and J alignments in extendAlignments minimalNOverlap in assembleParti...
Major changes Major review of affine alignment algorithms Minor changes Fix for MiXCR script for ...
Fixes rare inconsistency in behaviour between paired-end and single-end aligners, clone assembler an...
Chain distribution is back in report file V/J chimera detection and elimination mechanism; new param...
Major changes New command assembleContigs for assembling longest possible contig TCR/IG receptor se...
Fixed bug with wrong V gene selection in assembleContigs. analyze doesn't use .clna when contig asse...
Additional fix for error in exportAlignments / exportClones with repeated non-parametrized options A...
Fixed problem with possibly incorrect clone-to-alignment mapping and clonotype sorting. The problem ...
Major review of all analysis steps for non-enriched libraries (RNA-Seq, etc...). Efficiency of TCR/I...
Fixes V/J/C oversplitting issue in noizy data Additional fix for empty block exception in assemble a...
This fixes problem with repeated CLI options in export VRegionWithP now is used as featureToAlign fo...
Major changes Additional check for the same V hits in merging sequences in assemblePartial Fix: lis...
Major changes Fixes clone oversplitting in assembleContigs in noizy (e.g. single-cell) data with su...
Fixes NPE in very rare cases with incompatible V gene selection for assembleContigs in case of parti...
Major fix for analyze action (wrong aligner paramters were used before) Also several minor fixes to ...
Minimal thresholds added for V and J alignments in extendAlignments minimalNOverlap in assembleParti...
Major changes Major review of affine alignment algorithms Minor changes Fix for MiXCR script for ...
Fixes rare inconsistency in behaviour between paired-end and single-end aligners, clone assembler an...
Chain distribution is back in report file V/J chimera detection and elimination mechanism; new param...
Major changes New command assembleContigs for assembling longest possible contig TCR/IG receptor se...
Fixed bug with wrong V gene selection in assembleContigs. analyze doesn't use .clna when contig asse...
Additional fix for error in exportAlignments / exportClones with repeated non-parametrized options A...
Fixed problem with possibly incorrect clone-to-alignment mapping and clonotype sorting. The problem ...
Major review of all analysis steps for non-enriched libraries (RNA-Seq, etc...). Efficiency of TCR/I...
Fixes V/J/C oversplitting issue in noizy data Additional fix for empty block exception in assemble a...
This fixes problem with repeated CLI options in export VRegionWithP now is used as featureToAlign fo...