Various performance improvements (using jemalloc, avoiding bound checks that cannot fail, enabling more compiler optimizations, avoid fetching irrelevant reads). In total, this did result in a 2-times speedup on our test data
⚠ BREAKING CHANGES Rename estimate tmb subcommand into estimate mutational-burden (#182) Features ...
3.19.3 (2023-01-15) Performance Improvements update to varlociraptor 5.6.1 (#189) (4c34c84
Features by default, use prior to guard absence or presence of variant but weight all decisions abo...
Performance Improvements various speed improvements for scenario evaluations (#212) (f865e1b
Bug Fixes temporarily disable performance optimization in realignment because it can lead to undere...
Features adaptive integration (speeding up the evaluation of complex scenarios) (#199) (8043f94) B...
Performance Improvements do not consider empty pileups for bias preprocessing (#214) (e9beec3
Fixed a bug in the new prior implementation that led to almost infinite filling of a result cache, l...
Allow parallelization via setting the number of threads. BCF output is now unsorted, and must be sor...
Generalized TMB plots to mutational burden plots (not tumor specific). Added a multi-sample variant ...
Features added ability to omit MAPQ adjustment for known variants (varlociraptor preprocess variant...
Features refinement of homopolymer error model (for increased specificity) (#246) (380245d) Bug Fi...
Features improved formula simplification for negations which can provide major speedups and fixes a...
Fixed allele frequency biases that occurred due to missed evidence when investigating breakends. Fix...
Features better homopolymer error detection (#226) (b95d03d) eliminate false positives and false ne...
⚠ BREAKING CHANGES Rename estimate tmb subcommand into estimate mutational-burden (#182) Features ...
3.19.3 (2023-01-15) Performance Improvements update to varlociraptor 5.6.1 (#189) (4c34c84
Features by default, use prior to guard absence or presence of variant but weight all decisions abo...
Performance Improvements various speed improvements for scenario evaluations (#212) (f865e1b
Bug Fixes temporarily disable performance optimization in realignment because it can lead to undere...
Features adaptive integration (speeding up the evaluation of complex scenarios) (#199) (8043f94) B...
Performance Improvements do not consider empty pileups for bias preprocessing (#214) (e9beec3
Fixed a bug in the new prior implementation that led to almost infinite filling of a result cache, l...
Allow parallelization via setting the number of threads. BCF output is now unsorted, and must be sor...
Generalized TMB plots to mutational burden plots (not tumor specific). Added a multi-sample variant ...
Features added ability to omit MAPQ adjustment for known variants (varlociraptor preprocess variant...
Features refinement of homopolymer error model (for increased specificity) (#246) (380245d) Bug Fi...
Features improved formula simplification for negations which can provide major speedups and fixes a...
Fixed allele frequency biases that occurred due to missed evidence when investigating breakends. Fix...
Features better homopolymer error detection (#226) (b95d03d) eliminate false positives and false ne...
⚠ BREAKING CHANGES Rename estimate tmb subcommand into estimate mutational-burden (#182) Features ...
3.19.3 (2023-01-15) Performance Improvements update to varlociraptor 5.6.1 (#189) (4c34c84
Features by default, use prior to guard absence or presence of variant but weight all decisions abo...
DOI
Add to ORKG