Polished TMB plots. Allow to omit insert size evidence. This is important for amplicon data, where indels do not impact insert size
Add support for inversions, deletions and breakends. Slightly modified CLI options
Features adaptive integration (speeding up the evaluation of complex scenarios) (#199) (8043f94) B...
Bug Fixes erroneous integral boundary adjustment when having small VAF intervals and only very few ...
Fixed handling of missing insert size information. This is now detected automatically. CLI fixes. Ad...
Improved TMB estimation plots, now offering three modes (hist, curve, and stratified), as well as be...
Features added ability to omit MAPQ adjustment for known variants (varlociraptor preprocess variant...
Generalized TMB plots to mutational burden plots (not tumor specific). Added a multi-sample variant ...
Features if present, parse EF tag and consider single end reads marked to entirely cover the origin...
Fix odds filtering arguments. Improved error messages. Improved insert size estimation. Use htslib 1...
Fixed allele frequency biases that occurred due to missed evidence when investigating breakends. Fix...
Auto-detect insert size when mapping primer sequences (@dlaehnemann). Improved schemas for config an...
Improvements to SNV and MNV calling: in case of reads with indels, perform a realignment to properly...
⚠ BREAKING CHANGES Rename estimate tmb subcommand into estimate mutational-burden (#182) Features ...
Features add experimental support for the estimation of contaminations (#319) (c8c607c
Bug Fixes temporarily disable performance optimization in realignment because it can lead to undere...
Add support for inversions, deletions and breakends. Slightly modified CLI options
Features adaptive integration (speeding up the evaluation of complex scenarios) (#199) (8043f94) B...
Bug Fixes erroneous integral boundary adjustment when having small VAF intervals and only very few ...
Fixed handling of missing insert size information. This is now detected automatically. CLI fixes. Ad...
Improved TMB estimation plots, now offering three modes (hist, curve, and stratified), as well as be...
Features added ability to omit MAPQ adjustment for known variants (varlociraptor preprocess variant...
Generalized TMB plots to mutational burden plots (not tumor specific). Added a multi-sample variant ...
Features if present, parse EF tag and consider single end reads marked to entirely cover the origin...
Fix odds filtering arguments. Improved error messages. Improved insert size estimation. Use htslib 1...
Fixed allele frequency biases that occurred due to missed evidence when investigating breakends. Fix...
Auto-detect insert size when mapping primer sequences (@dlaehnemann). Improved schemas for config an...
Improvements to SNV and MNV calling: in case of reads with indels, perform a realignment to properly...
⚠ BREAKING CHANGES Rename estimate tmb subcommand into estimate mutational-burden (#182) Features ...
Features add experimental support for the estimation of contaminations (#319) (c8c607c
Bug Fixes temporarily disable performance optimization in realignment because it can lead to undere...
Add support for inversions, deletions and breakends. Slightly modified CLI options
Features adaptive integration (speeding up the evaluation of complex scenarios) (#199) (8043f94) B...
Bug Fixes erroneous integral boundary adjustment when having small VAF intervals and only very few ...