Body weight and GTT profiles of C57 substrains of both sexes.

Body weight (A) of male and female animals belonging to five C57 substrains i.e., 6JCrl (black with shaded pattern), 6JOlaEnv (blue), 6JRccEnv (maroon), 6NCrl (green with shaded pattern), 6NEnv (purple). Blood glucose levels (mmol/L) measured every 15 minutes (left) and total glycaemic excursion measured as total area under curve (right) during the GTT for females (B) and male (C) C57 substrains. All data sets visualised as scatter plots with mean ± SD with significances for displayed on graph as: ** = p<0.01, * = p<0.05 (Tukey’s post-hoc test), p<0.09 in italics for marginal significances (see text for statistics). Key for substrains displayed at bottom of figure with Crl animals (J/N) having shaded pattern to distinguish from Env.