A. Average percentage of ligated integrins varying timestep, in the presence (fiber) or absence (no fiber) of actin bundling. When present, a fiber of 300 nm width is used. B. Average percentage of ligated integrins varying timestep, and using k = 0.2 pN/nm and k = 0.4 pN/nm. An actomyosin force of 20 pN is applied to ligated integrins in the fiber area, considering a fiber width of 300 nm. All data are computed between 100–500 s, from 3 independent runs. Errorbars indicate standard error from the mean. (TIFF)</p
(a) Actin filaments status during the whole evolution for the case of active gel. We have 25 filamen...
Average lifetime of gaps ratio (divided by control case) in first column and average size in second ...
<p>A) Actin (red) and nuclei (blue) in low glucose cells with VEGF blocked for 24 hours with a neutr...
A. Average percentage of ligated integrins varying the width of the actin fiber and using Pbundling ...
A-B. Distribution of the total time spent by integrins in the ligated state, in different conditions...
A. Snapshots of ligand-bound integrins (magenta) at 200 s of simulations, using no fiber (left) and ...
A. Distribution of the percentage of ligated integrins in different conditions of bundling and Fmyo ...
A. The average fraction of ligand-bound integrins varying Pbundling between 0–1, and Fmyo between 0–...
A. A heatmap of the average percentage of ligand bound integrins varying substrate stiffness, k, bet...
A. Distribution of force on ligated integrins using actin flow velocity of 0, 10, 30, and 100 nm/s, ...
(a) Status of actin filaments during the whole simulation time. For this system the attachment rate ...
A. Schematics of the 2D computational model. The domain consists of a grid of ideal springs (gray pa...
(a) Representative confocal images of HUVECs suspended in 3D biopolymer networks of fibrin (3 mg/mL)...
(A) Sequence of images from a simulated time lapse of 1,000 actin filaments (red) and 5,000 myosin m...
<p>Simulations and experimental data for a small and fast length step, , applied to a muscle fiber i...
(a) Actin filaments status during the whole evolution for the case of active gel. We have 25 filamen...
Average lifetime of gaps ratio (divided by control case) in first column and average size in second ...
<p>A) Actin (red) and nuclei (blue) in low glucose cells with VEGF blocked for 24 hours with a neutr...
A. Average percentage of ligated integrins varying the width of the actin fiber and using Pbundling ...
A-B. Distribution of the total time spent by integrins in the ligated state, in different conditions...
A. Snapshots of ligand-bound integrins (magenta) at 200 s of simulations, using no fiber (left) and ...
A. Distribution of the percentage of ligated integrins in different conditions of bundling and Fmyo ...
A. The average fraction of ligand-bound integrins varying Pbundling between 0–1, and Fmyo between 0–...
A. A heatmap of the average percentage of ligand bound integrins varying substrate stiffness, k, bet...
A. Distribution of force on ligated integrins using actin flow velocity of 0, 10, 30, and 100 nm/s, ...
(a) Status of actin filaments during the whole simulation time. For this system the attachment rate ...
A. Schematics of the 2D computational model. The domain consists of a grid of ideal springs (gray pa...
(a) Representative confocal images of HUVECs suspended in 3D biopolymer networks of fibrin (3 mg/mL)...
(A) Sequence of images from a simulated time lapse of 1,000 actin filaments (red) and 5,000 myosin m...
<p>Simulations and experimental data for a small and fast length step, , applied to a muscle fiber i...
(a) Actin filaments status during the whole evolution for the case of active gel. We have 25 filamen...
Average lifetime of gaps ratio (divided by control case) in first column and average size in second ...
<p>A) Actin (red) and nuclei (blue) in low glucose cells with VEGF blocked for 24 hours with a neutr...