pTDP-43 aggregates colocalize with GR repeat.
- Yoshitaka Tamaki (14573781)
- Jay P. Ross (7865792)
- Paria Alipour (14044499)
- Charles-Étienne Castonguay (14573784)
- Boting Li (14573787)
- Helene Catoire (7865783)
- Daniel Rochefort (7865786)
- Makoto Urushitani (108130)
- Ryosuke Takahashi (108123)
- Joshua A. Sonnen (11916716)
- Stefano Stifani (183044)
- Patrick A. Dion (7865801)
- Guy A. Rouleau (105556)
Publication date
February 2023
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Dot blot analysis of sarkosyl-insoluble protein extracts from non-ALS control (control 1) and C9orf72-ALS spinal cords (patient 3), immunoblotted with GR repeat antibody. (B) Immunofluorescence images of OrgALS cerebral organoids double-labelled with pTDP-43 and GR repeat proteins at 8 weeks post injection of protein extracts from C9orf72-ALS (patient 3) (upper panels) or non-C9orf72-ALS (patient 4) (lower panels). Scale bars = 10 μm. (TIF)</p
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