Fig 5 -

Time-growth (a) and time-kill (Ampicillin at 100 μg/mL) (b) experiments for generation of data to assess ton/toff for design of pulse dosing. 95%-confidence bands are shown. The slope of the cyan straight line (a) indicates the initial slope of the blue line and corresponds to Kn,off/ln(10), whereas the blue line slope (b) is Kn,on/ln(10).