The profound and unique institutional and economic processes which characterise the historic period Europe is facing and will face call for appropriate methodologies to forecast the impact of these processes on Europe and its territory. Few regional econometric models as the basis of forecasting exercises have been developed, either replicating national macroeconomic models, or through complex systems of equations for each region that are linked to both the national aggregate economy and to the other regional economies through input—output technical coefficients that determine intra- and inter-regional trade and output. This paper presents a new regional forecasting model, labelled MASST (macroeconomic, sectoral, social and territorial), ...