Among the vast number of regional growth forecasting models, the past fifteen years witnessed the emergence of the MAcroeconomic, Sectoral, Social, Territorial (MASST) model. The MASST model aims at merging macroeconomic elements with territorial features for forecasting regional growth trajectories. In fact, the model was created with the aim to overcome the dichotomous approaches interpreting regional growth either as a bottom-up process without macroeconomic elements, or a top-down one, whereby national growth rates are reassigned to regions according to their weights, neglecting any role to regional propulsive forces. The model has now reached its fourth generation. The aim of this paper is first to present a discussion of the theoretic...