This paper concerns the numerical and experimental characterization ofthe static and fatigue strength of a flat stiffened panel, designed as a fiber metal laminates (FML) and made of Aluminum alloy and Fiber Glass FRP. The panel is full scale and was tested under both static and fatigue biaxial loads, applied by means of an in house designed and built multi-axial fatigue machine. The static test is simulated by the Boundary Element Method (BEM) in a two-dimensional approach (only allowance for membrane stresses). The strain gauge outcomes are compared with corresponding numerical results, getting a satisfactory correlation. After the static test, an initial notch is created in the panel and the aforementioned biaxial fatigue load is applie...