Background. Fibroids are the most common benign tumors in women of reproductive age. The prevalence is approximately 2%, ranging from 0.1% to 12.5. Most pregnant women with uterine myomas do not experience any symptoms, whereas 10–30% develop complications. Objective of the study. Appreciating the optimal timing of myomectomy during pregnancy. Results. Patient X term of pregnancy 23 weeks, hospitalized with acute pain under the left and right costal rim, irradiation in the bilateral lumbar region and with signs of peritoneal irritation. On the left side of the uterus, there is a hard, painful, round mass, measuring 11x7 cm. The USG found the viability of the fetus and the subserosal myoma, dimensions 129x76x78 cm with necrosis area. ...