A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro for their reversal activity in human mammary carcinoma MDR cell line MCF7-R. One of the new taxoids showed to be active at 0.1 microM when tested in combination with paclitaxel
Paclitaxel, a natural secondary metabolite isolated and purified from the bark of the Taxus tree, is...
The diterpenoid paclitaxel (Taxol™) is one of the most effective anticancer drugs, used against a wi...
An efficient synthetic strategy has been developed to prepare an oxygenated analog of Taxuspine X. M...
A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro f...
Starting from 10-deacetylbaccatin 111 (7), the 2-debenzoyl-2-m-methoxybenzoyl analogs of the newer g...
Novel second-generation taxoids with systematic modifications at the C2, C10, and C3’N positions wer...
The taxuyunnanine C (Tc) was greatly enhanced when Taxus chinensis cell cultures were elicited by me...
The production of taxuyunnanine C (Tc) (2α,5α,10β,14β-tetraacetoxytaxa-4(20),11(12)-diene) was signi...
Paclitaxel (Taxol©) is one of the most effective anticancer agents known to man to date. It acts by ...
The production of taxuyunnanine C (Tc) (2 alpha, 5 alpha, 10 beta, 14 beta-tetraacetoxytaxa-4(20), 1...
© 2017 Mikhail V. Pugachev et al. A series of trans-6-phenylethenyl substituted pyridoxine derivativ...
Human society has benefited greatly from plant secondary metabolites, often utilizing a variety of c...
Paclitaxel, a diterpene natural product from the Pacific Yew tree, Taxus brevifolia, has emerged as ...
[[abstract]]Various dietary antioxidants, including vitamins, flavonoids, curcumin, and a coumarin, ...
The development of resistance to multiple structurally unrelated drugs is considered to be one of th...
Paclitaxel, a natural secondary metabolite isolated and purified from the bark of the Taxus tree, is...
The diterpenoid paclitaxel (Taxol™) is one of the most effective anticancer drugs, used against a wi...
An efficient synthetic strategy has been developed to prepare an oxygenated analog of Taxuspine X. M...
A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro f...
Starting from 10-deacetylbaccatin 111 (7), the 2-debenzoyl-2-m-methoxybenzoyl analogs of the newer g...
Novel second-generation taxoids with systematic modifications at the C2, C10, and C3’N positions wer...
The taxuyunnanine C (Tc) was greatly enhanced when Taxus chinensis cell cultures were elicited by me...
The production of taxuyunnanine C (Tc) (2α,5α,10β,14β-tetraacetoxytaxa-4(20),11(12)-diene) was signi...
Paclitaxel (Taxol©) is one of the most effective anticancer agents known to man to date. It acts by ...
The production of taxuyunnanine C (Tc) (2 alpha, 5 alpha, 10 beta, 14 beta-tetraacetoxytaxa-4(20), 1...
© 2017 Mikhail V. Pugachev et al. A series of trans-6-phenylethenyl substituted pyridoxine derivativ...
Human society has benefited greatly from plant secondary metabolites, often utilizing a variety of c...
Paclitaxel, a diterpene natural product from the Pacific Yew tree, Taxus brevifolia, has emerged as ...
[[abstract]]Various dietary antioxidants, including vitamins, flavonoids, curcumin, and a coumarin, ...
The development of resistance to multiple structurally unrelated drugs is considered to be one of th...
Paclitaxel, a natural secondary metabolite isolated and purified from the bark of the Taxus tree, is...
The diterpenoid paclitaxel (Taxol™) is one of the most effective anticancer drugs, used against a wi...
An efficient synthetic strategy has been developed to prepare an oxygenated analog of Taxuspine X. M...
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