EBV gene expression in T2 virus- versus T1 virus-infected NOKs.

RNA-seq reads from NOKs cells infected with T1 or T2 viruses were aligned to the T1 or T2 EBV genomes, respectively. For each strain, wiggle tracks of normalized read depth were normalized and plotted (black) with standard errors (gray). Annotation tracks for type 1 and type 2 viruses showing latent (blue) genes and lytic (black) genes were generated using UCSC genome browsers and displayed above. The BXLF1 gene (shown in green) was disrupted by insertion of a G418R/GFP cassette and transcription in this region arises as a result of the promoters within this cassette. (TIF)