Additional file 1 of Super-enhancer-associated INSM2 regulates lipid metabolism by modulating mTOR signaling pathway in neuroblastoma
- Haibo Cao (267918)
- Ran Zhuo (395817)
- Zimu Zhang (5744795)
- Jianwei Wang (128689)
- Yanfang Tao (9694025)
- Randong Yang (13807828)
- Xinyi Guo (3755509)
- Yanling Chen (498235)
- Siqi Jia (8332686)
- Ye Yao (348477)
- Pengcheng Yang (104213)
- Juanjuan Yu (2172736)
- Wanyan Jiao (13815323)
- Xiaolu Li (586812)
- Fang Fang (38179)
- Yi Xie (12835)
- Gen Li (743590)
- Di Wu (23906)
- Hairong Wang (1694704)
- Chenxi Feng (5891462)
- Yunyun Xu (516217)
- Zhiheng Li (525468)
- Jian Pan (10689341)
- Jian Wang (5901)
Publication date
September 2022
DOIAbstract
Additional file 1: Fig.S1. INSM2 expression in GN tissue and NB tissue (GSE147635).Fig. S2. SK-N-BE(2) and SK-N-SHcells were infected with sh-NC or sh-INSM2 or sh-INSM2+INSM2. The cells were harvestedfor CCK-8 colorimetric assay. Fig. S3. IHCanalysis for CD31. Fig.S4. Lipid metabolism-related geneFASN affects the growth of NB. Fig.S5. A KEGGpathway analysis of the differentially expressed genes. B-C qPCR and Western blot analysis of the expression for oncogenes of NB (MYCN andANXA2) after knockdown of INSM2. Fig. S6. A-D Kaplan-Meier curvesindicating the survival of NB patients with high or low FASN, ACC, ACSS2 andSCD expression
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