Fig 5 -

(a) Overview of CYP1B1 wild type protein in ribbon-presentation (b-l) In-silico protein prediction regarding variant protein structures for all detected variants by HOPE software. (b-l) i: for each variant show the position of amino acid in protein structure. (b-l) ii: for each detected variant show the zoomed in change in protein structure due to each respective variant (Wild type amino acid residue is colored as green while mutant is colored as red).