Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase

Lo, Chia-Hsiang

[[abstract]]We present here how two amino acid residues in the first helix distal from the main dime...

Crystal structure analysis on the tyrosine-regulated 3-Deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae

König, Verena

October 2002

Im Gegensatz zu Säugetieren sind Prokaryonten, Hefen, Algen und Pflanzen in der Lage, di...

Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure

Chen, Anjun
Dale Poulter, C.
Kroon, Paulos A.

January 1994

Isoprenyl diphosphate synthases are ubiquitous enzymes that catalyze the basic chain‐elongation reac...

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh, K
Dunford, J
Bunkoczi, G
Russell, R
Oppermann, U

January 2006

Modification of GTPases with isoprenoid molecules derived from geranylgeranyl pyrophosphate or farne...

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.

Han, X

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Figure S2 from Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy

Andrew C. Pham (17726970)
Sarah A. Holstein (12068778)
Gloria E.O. Borgstahl (17726973)

January 2024

AlphaFold model of an hGGDPS monomer (hGGDPSAF) and sequence alignment of hGGDPS with yGGDPS. A. Reg...

Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.

Artz, JD
Wernimont, AK
Dunford, JE
Schapira, M
Dong, A
Zhao, Y
Lew, J
Russell, RG
Ebetino, FH
Oppermann, U
Hui, R

February 2011

We present here a study of a eukaryotic trans-prenylsynthase from the malaria pathogen Plasmodium vi...

Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.

Chang, TH

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.

Ko, TP

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase.

Lo, CH

[[sponsorship]]生物醫學科學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/...

Figure S1 from Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy

Andrew C. Pham (17726970)
Sarah A. Holstein (12068778)
Gloria E.O. Borgstahl (17726973)

January 2024

Higher-order organization of GGDPS subunits. A. The dimer interface between chains A (green) and B (...

Constructing Tailored Isoprenoid Products by Structure-Guided Modification of Geranylgeranyl Reductase

Kung, Yan
McAndrew, Ryan P.
Xie, Xinkai
Liu, Charlie C.
Pereira, Jose H.
Adams, Paul D.
Keasling, Jay D.

July 2014

SummaryThe archaeal enzyme geranylgeranyl reductase (GGR) catalyzes hydrogenation of carbon-carbon d...

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.

Chen, C K-M

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase

Lo, Chia-Hsiang

[[abstract]]We present here how two amino acid residues in the first helix distal from the main dime...

Crystal structure analysis on the tyrosine-regulated 3-Deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae

König, Verena

October 2002

Im Gegensatz zu Säugetieren sind Prokaryonten, Hefen, Algen und Pflanzen in der Lage, di...

Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure

Chen, Anjun
Dale Poulter, C.
Kroon, Paulos A.

January 1994

Isoprenyl diphosphate synthases are ubiquitous enzymes that catalyze the basic chain‐elongation reac...

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh, K
Dunford, J
Bunkoczi, G
Russell, R
Oppermann, U

January 2006

Modification of GTPases with isoprenoid molecules derived from geranylgeranyl pyrophosphate or farne...

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.

Han, X

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Figure S2 from Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy

Andrew C. Pham (17726970)
Sarah A. Holstein (12068778)
Gloria E.O. Borgstahl (17726973)

January 2024

AlphaFold model of an hGGDPS monomer (hGGDPSAF) and sequence alignment of hGGDPS with yGGDPS. A. Reg...

Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.

Artz, JD
Wernimont, AK
Dunford, JE
Schapira, M
Dong, A
Zhao, Y
Lew, J
Russell, RG
Ebetino, FH
Oppermann, U
Hui, R

February 2011

We present here a study of a eukaryotic trans-prenylsynthase from the malaria pathogen Plasmodium vi...

Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.

Chang, TH

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.

Ko, TP

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase.

Lo, CH

[[sponsorship]]生物醫學科學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/...

Figure S1 from Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy

Andrew C. Pham (17726970)
Sarah A. Holstein (12068778)
Gloria E.O. Borgstahl (17726973)

January 2024

Higher-order organization of GGDPS subunits. A. The dimer interface between chains A (green) and B (...

Constructing Tailored Isoprenoid Products by Structure-Guided Modification of Geranylgeranyl Reductase

Kung, Yan
McAndrew, Ryan P.
Xie, Xinkai
Liu, Charlie C.
Pereira, Jose H.
Adams, Paul D.
Keasling, Jay D.

July 2014

SummaryThe archaeal enzyme geranylgeranyl reductase (GGR) catalyzes hydrogenation of carbon-carbon d...

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.

Chen, C K-M

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase

Lo, Chia-Hsiang

[[abstract]]We present here how two amino acid residues in the first helix distal from the main dime...

Crystal structure analysis on the tyrosine-regulated 3-Deoxy-D-arabino-heptulosonate-7-phosphate synthase from Saccharomyces cerevisiae

König, Verena

October 2002

Im Gegensatz zu Säugetieren sind Prokaryonten, Hefen, Algen und Pflanzen in der Lage, di...

Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure

Chen, Anjun
Dale Poulter, C.
Kroon, Paulos A.

January 1994

Isoprenyl diphosphate synthases are ubiquitous enzymes that catalyze the basic chain‐elongation reac...

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Abstract

Extracted data

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Abstract

Extracted data

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