Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.

Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

Krajewski, Wojciech W.
Collins, Ruairi
Holmberg-Schiavone, Lovisa
Jones, T. Alwyn
Karlberg, Tobias
Mowbray, Sherry L.

January 2008

Glutamine synthetase (GS) catalyzes the ligation of glutamate and ammonia to form glutamine, with co...

Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis

Ballut, Lionel
Violot, Sébastien
Galisson, Frédéric
Gonçalves, Isabelle R.
Martin, Juliette
Shivakumaraswamy, Santosh
Carrique, Loïc
Balaram, Hemalatha
Aghajari, Nushin

July 2022

International audienceGlutamine amidotransferases, enzymes that transfer nitrogen from Gln to variou...

Fig. 1 in Site-directed mutagenesis of β sesquiphellandrene synthase enhances enzyme promiscuity

Ker, De-Sheng
Chan, Kok Gan
Othman, Roohaida
Hassan, Maizom
Ng, Chyan Leong

May 2020

Fig. 1. Superimposition of PmSTS homology model (green) with the crystal structure of Nicotiana taba...

Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh, Kathryn L
Dunford, James E
Bunkoczi, Gabor
Russell, R Graham G
Oppermann, Udo

August 2006

Modification of GTPases with isoprenoid molecules derived from geranylgeranyl pyrophosphate or farne...

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Chang, TH

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.

Chang, SY

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases.

Cao, R

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure, function and inhibition of GcpE, FPPS and GGPPS: targeting isoprenoid biosynthesis for drug discovery

Liu, Yi-Liang

December 2012

IspG, farnesyl diphosphate synthase (FPPS) and geranylgeranyl diphosphate synthase (GGPPS) are enzym...

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.

Han, X

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Design of novel inhibitors for human geranylgeranyl pyrophosphate synthase

Ta, Viviane

January 2015

Human geranylgeranyl pyrophosphate synthase (hGGPPS) is an enzyme in the mevalonate pathway that cat...

Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

Krajewski, Wojciech W.
Collins, Ruairi
Holmberg-Schiavone, Lovisa
Jones, T. Alwyn
Karlberg, Tobias
Mowbray, Sherry L.

January 2008

Glutamine synthetase (GS) catalyzes the ligation of glutamate and ammonia to form glutamine, with co...

Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis

Ballut, Lionel
Violot, Sébastien
Galisson, Frédéric
Gonçalves, Isabelle R.
Martin, Juliette
Shivakumaraswamy, Santosh
Carrique, Loïc
Balaram, Hemalatha
Aghajari, Nushin

July 2022

International audienceGlutamine amidotransferases, enzymes that transfer nitrogen from Gln to variou...

Fig. 1 in Site-directed mutagenesis of β sesquiphellandrene synthase enhances enzyme promiscuity

Ker, De-Sheng
Chan, Kok Gan
Othman, Roohaida
Hassan, Maizom
Ng, Chyan Leong

May 2020

Fig. 1. Superimposition of PmSTS homology model (green) with the crystal structure of Nicotiana taba...

Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh, Kathryn L
Dunford, James E
Bunkoczi, Gabor
Russell, R Graham G
Oppermann, Udo

August 2006

Modification of GTPases with isoprenoid molecules derived from geranylgeranyl pyrophosphate or farne...

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Chang, TH

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase.

Hsieh, FL

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.

Chang, SY

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases.

Cao, R

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Structure, function and inhibition of GcpE, FPPS and GGPPS: targeting isoprenoid biosynthesis for drug discovery

Liu, Yi-Liang

December 2012

IspG, farnesyl diphosphate synthase (FPPS) and geranylgeranyl diphosphate synthase (GGPPS) are enzym...

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.

Han, X

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis

Guo, RT

[[sponsorship]]生物化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Ga...

Design of novel inhibitors for human geranylgeranyl pyrophosphate synthase

Ta, Viviane

January 2015

Human geranylgeranyl pyrophosphate synthase (hGGPPS) is an enzyme in the mevalonate pathway that cat...

Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

Krajewski, Wojciech W.
Collins, Ruairi
Holmberg-Schiavone, Lovisa
Jones, T. Alwyn
Karlberg, Tobias
Mowbray, Sherry L.

January 2008

Glutamine synthetase (GS) catalyzes the ligation of glutamate and ammonia to form glutamine, with co...

Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis

Ballut, Lionel
Violot, Sébastien
Galisson, Frédéric
Gonçalves, Isabelle R.
Martin, Juliette
Shivakumaraswamy, Santosh
Carrique, Loïc
Balaram, Hemalatha
Aghajari, Nushin

July 2022

International audienceGlutamine amidotransferases, enzymes that transfer nitrogen from Gln to variou...

Fig. 1 in Site-directed mutagenesis of β sesquiphellandrene synthase enhances enzyme promiscuity

Ker, De-Sheng
Chan, Kok Gan
Othman, Roohaida
Hassan, Maizom
Ng, Chyan Leong

May 2020

Fig. 1. Superimposition of PmSTS homology model (green) with the crystal structure of Nicotiana taba...

Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.

Abstract

Extracted data

Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.

Abstract

Extracted data

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