Add to ORKGCholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized with antisense oligonucleotides to study their incorporation in cationic liposomes together with the influence of this dendrimeric delivery system on biological activity. Electrostatic interactions seem to play the most important role during complexation with cationic lipids. This oligonucleotide formulation gives a small but significant increase in the inhibition of P-glycoprotein expression in a cellular system
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
Submicron unilamellar cationic liposomes constructed from equimolar amounts of a cholesteryl cytofec...
The ability of oligonucleotides to silence specific genes or inhibit the biological activity of spec...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
The ability of oligonucleotides to silence specific genes or inhibit the biological activity of spec...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
Submicron unilamellar cationic liposomes constructed from equimolar amounts of a cholesteryl cytofec...
The ability of oligonucleotides to silence specific genes or inhibit the biological activity of spec...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
The ability of oligonucleotides to silence specific genes or inhibit the biological activity of spec...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
Submicron unilamellar cationic liposomes constructed from equimolar amounts of a cholesteryl cytofec...
The ability of oligonucleotides to silence specific genes or inhibit the biological activity of spec...