Add to ORKGThis thesis focuses on improving our understanding of antisense action. To do so, an investigation was carried out of the entry pathway and intracellular processing of cationic lipidsas delivery agents for ODNs and nucleic acids. In addition, the delivery potential of such a carrier for proteins was investigated
There has been great interest recently in therapeutic use of nucleic acids including genes, ribozyme...
Antisense oligonucleotides were potentially very powerful tools to modulate gene expression. Progres...
The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
For more than two decades, antisense oligonucleotides (ODNs) have been used to modulate gene express...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
Successful application of antisense oligonucleotides (ODNs) in cell biology and therapy will depend ...
Attaining the full therapeutic utility of antisense and siRNA oligonucleotides will require understa...
Antisense oligonucleotides efficiently inhibit gene expression in vitro; however, the successful the...
Antisense oligonucleotides (ASOs), which are synthetic single-stranded nucleic acids, could enter li...
AbstractPhosphorothioate oligodeoxynudeotides, designed as nuclease-resistant antisense agents, appe...
Antisense oligodesoxynucleotide strategies in renal and cardiovascular disease. Antisense oligodesox...
Abstract: Antisense oligonucleotides (As-ODNs) are single stranded, synthetically prepared strands o...
There has been great interest recently in therapeutic use of nucleic acids including genes, ribozyme...
Antisense oligonucleotides were potentially very powerful tools to modulate gene expression. Progres...
The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
This thesis focuses on improving our understanding of antisense action. To do so, an investigation w...
Cholesterol modified mono-, di-, and tetrameric oligonucleotides were synthesized and hybridized wit...
For more than two decades, antisense oligonucleotides (ODNs) have been used to modulate gene express...
There is mounting interest in developing antisense and siRNA oligonucleotides into therapeutic entit...
Successful application of antisense oligonucleotides (ODNs) in cell biology and therapy will depend ...
Attaining the full therapeutic utility of antisense and siRNA oligonucleotides will require understa...
Antisense oligonucleotides efficiently inhibit gene expression in vitro; however, the successful the...
Antisense oligonucleotides (ASOs), which are synthetic single-stranded nucleic acids, could enter li...
AbstractPhosphorothioate oligodeoxynudeotides, designed as nuclease-resistant antisense agents, appe...
Antisense oligodesoxynucleotide strategies in renal and cardiovascular disease. Antisense oligodesox...
Abstract: Antisense oligonucleotides (As-ODNs) are single stranded, synthetically prepared strands o...
There has been great interest recently in therapeutic use of nucleic acids including genes, ribozyme...
Antisense oligonucleotides were potentially very powerful tools to modulate gene expression. Progres...
The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great...