Summary of strain-, dose- and tissue-dependent processes.

Summary of parameters that were distinct between different infection scenarios. Parameters consistently different included (A) strain-dependent virus production rates (p), (B-C) dose- and tissue-dependent infected cell clearance rates (δd/Kδ). Other parameters shown include the initial number of target cells (T0), virus clearance (c), and virus infection (β). Subscripts “M” and “P” denote the rSeV-luc(M-F*) (“M-F”) and rSeV-luc(P-M) (“P-M”) viruses, respectively. Subscripts “L”, “T”, and “N” denote the lung, trachea, and nasopharynx, respectively. Subscripts “H” and “S” denote high d/v and low d/v, respectively.