Immunostaining of testicular sections for PNA (red) and SYCP3 (green) from 10-week-old Mtl5+/+, Mtl5c-mu/c-mu, and Mtl5-/- mice. Nuclei were counterstained with Hoechst 33342 (grey). The cells in the white dotted boxes are enlarged aside. Scale bars, 50 μm. (TIF)</p
<p>(A) Sections of testes of WT mice and deficient mice (12 weeks old; <i>n</i> = 10 per group) were...
(A) Diagram (top) and nucleotide sequence (bottom) of mouse Mtl5 locus taken from the Ensemble datab...
<p>Representative histological sections of testes of +/+ (left panels) and −/− (two right panels) mi...
(A) Testis morphology, (B) Ratios of testis/body weight and (C) Epididymal sperm counts of 10-week-o...
(A) Immunostaining of SYCP3 (red), H1t (green), and γH2AX (blue) on pachytene spermatocytes from 10-...
H-E staining on testicular sections from control, Mtl5c-mu/c-mu and Mtl5-/- mice at indicated age. R...
Immunostaining and quantification of RPA2 (A, B) and DMC1 (C, D) in 10-week-old Mtl5+/+, Mtl5c-mu/c-...
<p>Testicular sections from wt (A and C) or TMF<sup>-/-</sup> (B and D) mice were subjected to TEM a...
(A) TUNEL assay on Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mouse testicular sections. Red, TUNEL positive...
(A) Testis sections were co-stained with anti-SCP3 (green) and anti-PLZF (cyan) antibodies in WT and...
<p>Testes from WT (A) and <i>Mus81<sup>−/−</sup></i> (B) mice were removed, weighed and photographed...
Background: Mll5 is currently a member of the Mll family of SET domain histone methyltransferase pro...
<p>(A-B) Propidium iodide based DNA flow cytometry analysis of testicular cell suspensions from wild...
<p>A. Semi-thin (8–10 micron) testes sections of 20 weeks old <i>Tysnd1</i><sup>+/+</sup> and <i>Tys...
(A, B, and C) Spermatogonia from DCUN1D1-/- mice have normal proliferative activity. Representative ...
<p>(A) Sections of testes of WT mice and deficient mice (12 weeks old; <i>n</i> = 10 per group) were...
(A) Diagram (top) and nucleotide sequence (bottom) of mouse Mtl5 locus taken from the Ensemble datab...
<p>Representative histological sections of testes of +/+ (left panels) and −/− (two right panels) mi...
(A) Testis morphology, (B) Ratios of testis/body weight and (C) Epididymal sperm counts of 10-week-o...
(A) Immunostaining of SYCP3 (red), H1t (green), and γH2AX (blue) on pachytene spermatocytes from 10-...
H-E staining on testicular sections from control, Mtl5c-mu/c-mu and Mtl5-/- mice at indicated age. R...
Immunostaining and quantification of RPA2 (A, B) and DMC1 (C, D) in 10-week-old Mtl5+/+, Mtl5c-mu/c-...
<p>Testicular sections from wt (A and C) or TMF<sup>-/-</sup> (B and D) mice were subjected to TEM a...
(A) TUNEL assay on Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mouse testicular sections. Red, TUNEL positive...
(A) Testis sections were co-stained with anti-SCP3 (green) and anti-PLZF (cyan) antibodies in WT and...
<p>Testes from WT (A) and <i>Mus81<sup>−/−</sup></i> (B) mice were removed, weighed and photographed...
Background: Mll5 is currently a member of the Mll family of SET domain histone methyltransferase pro...
<p>(A-B) Propidium iodide based DNA flow cytometry analysis of testicular cell suspensions from wild...
<p>A. Semi-thin (8–10 micron) testes sections of 20 weeks old <i>Tysnd1</i><sup>+/+</sup> and <i>Tys...
(A, B, and C) Spermatogonia from DCUN1D1-/- mice have normal proliferative activity. Representative ...
<p>(A) Sections of testes of WT mice and deficient mice (12 weeks old; <i>n</i> = 10 per group) were...
(A) Diagram (top) and nucleotide sequence (bottom) of mouse Mtl5 locus taken from the Ensemble datab...
<p>Representative histological sections of testes of +/+ (left panels) and −/− (two right panels) mi...