(A) Immunostaining of SYCP3 (red), H1t (green), and γH2AX (blue) on pachytene spermatocytes from 10-week-old Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mice. N, H1t-negative;P, H1t-positive. (B) The percentages of H1t-negative pachytene spermatocytes in 10-week-old Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mice. Numbers in the brackets indicate the number of counted cells. Data are presented as mean ± SEM. P values were analyzed by One-way ANOVA. ****p0.05. Scale bars, 10 μm. (TIF)</p
<p>Immunodetection of SCP3 (red) and γH2AX (green) in <i>TG-Ercc1</i> (A–C), <i>Msh2</i> (E–G) and <...
(A, B, and C) Spermatogonia from DCUN1D1-/- mice have normal proliferative activity. Representative ...
<p>(<b>A)</b> Immunostaining of SYCP3 and D27C4 (H2AK119ub) on wild-type meiotic chromosome spreads....
(A) Testis morphology, (B) Ratios of testis/body weight and (C) Epididymal sperm counts of 10-week-o...
<p>A Immunofluoresence labeling of histological sections for anti-γH2A.X (red) with DAPI (blue) coun...
<p>Immunofluorescence staining for SYCP3 (red), RAD51 (green) and H1T (blue) in control and <i>Mof</...
Immunostaining and quantification of RPA2 (A, B) and DMC1 (C, D) in 10-week-old Mtl5+/+, Mtl5c-mu/c-...
H-E staining on testicular sections from control, Mtl5c-mu/c-mu and Mtl5-/- mice at indicated age. R...
Immunostaining of testicular sections for PNA (red) and SYCP3 (green) from 10-week-old Mtl5+/+, Mtl5...
<p>A. Immunofluorescence with SYCP3 (red) and BRCA1 (green) antibodies in control and <i>Mof</i> cKO...
<p>Upper panels, immunofluorescence labeling of histological sections for SYCP3 (red) and DAPI (blue...
<p>(a) Representative pachytene wild-type and <i>Hfm1<sup>−/−</sup></i> spermatocytes stained with S...
<p>(A) Apoptotic <i>Trip13</i><sup><i>mod/mod</i></sup> spermatocyte showing the axial element prote...
<p>(A) Timeline of mouse spermatogenesis, with blue lines and tan histograms representing developmen...
(A) TUNEL assay on Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mouse testicular sections. Red, TUNEL positive...
<p>Immunodetection of SCP3 (red) and γH2AX (green) in <i>TG-Ercc1</i> (A–C), <i>Msh2</i> (E–G) and <...
(A, B, and C) Spermatogonia from DCUN1D1-/- mice have normal proliferative activity. Representative ...
<p>(<b>A)</b> Immunostaining of SYCP3 and D27C4 (H2AK119ub) on wild-type meiotic chromosome spreads....
(A) Testis morphology, (B) Ratios of testis/body weight and (C) Epididymal sperm counts of 10-week-o...
<p>A Immunofluoresence labeling of histological sections for anti-γH2A.X (red) with DAPI (blue) coun...
<p>Immunofluorescence staining for SYCP3 (red), RAD51 (green) and H1T (blue) in control and <i>Mof</...
Immunostaining and quantification of RPA2 (A, B) and DMC1 (C, D) in 10-week-old Mtl5+/+, Mtl5c-mu/c-...
H-E staining on testicular sections from control, Mtl5c-mu/c-mu and Mtl5-/- mice at indicated age. R...
Immunostaining of testicular sections for PNA (red) and SYCP3 (green) from 10-week-old Mtl5+/+, Mtl5...
<p>A. Immunofluorescence with SYCP3 (red) and BRCA1 (green) antibodies in control and <i>Mof</i> cKO...
<p>Upper panels, immunofluorescence labeling of histological sections for SYCP3 (red) and DAPI (blue...
<p>(a) Representative pachytene wild-type and <i>Hfm1<sup>−/−</sup></i> spermatocytes stained with S...
<p>(A) Apoptotic <i>Trip13</i><sup><i>mod/mod</i></sup> spermatocyte showing the axial element prote...
<p>(A) Timeline of mouse spermatogenesis, with blue lines and tan histograms representing developmen...
(A) TUNEL assay on Mtl5+/+, Mtl5c-mu/c-mu and Mtl5-/- mouse testicular sections. Red, TUNEL positive...
<p>Immunodetection of SCP3 (red) and γH2AX (green) in <i>TG-Ercc1</i> (A–C), <i>Msh2</i> (E–G) and <...
(A, B, and C) Spermatogonia from DCUN1D1-/- mice have normal proliferative activity. Representative ...
<p>(<b>A)</b> Immunostaining of SYCP3 and D27C4 (H2AK119ub) on wild-type meiotic chromosome spreads....