Bestimmung des Adsorptionskoeffizienten organischer Chemikalien mit der Hochdruck-Fluessigkeits-Chromatographie Abschlussbericht

It was the aim of the research project to develop and improve a screening method for the determination of the adsorption coefficient K_O_C in soil, which can be proposed as OECD Test Guideline for the base set. For the elaboration of the HPLC-Screening method the following subtopics had to be considered: selection of available appropriate reference substances; testing of different stationary and mobile phases including immobilized humic acids and clay minerals; determination of the feasibility and limits of the method; comparison of the HPLC-Screening Method with other screening methods; validation of the method by a ring test; proposal of a draft test guideline. OECD has already prepared a proposal for a new guideline. (orig)Available from TIB Hannover: RN 8908(94-072) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman