The Oscurusciuto rock shelter (southern Italy) is crucial for the understanding of Neanderthals’ subsistence and settlement strategies as it contains a ~ 6-m-thick reliable deposit made up of several Middle Palaeolithic levels. This paper focuses on level SU 14, a 60-cm-thick deposit of volcanic tephra containing traces of human occupation only in the few upper centimetres. Geochemical and mineralogical features of SU 14 deposits allowed their correlation to the ‘Mount Epomeo Green Tuff’ eruption, which came from Ischia volcano and dated to ~ 55,000 years bp. The pyroclastic materials injected into the atmosphere caused an ash fall-out over a large part of southern Italy, resulting in the alteration of ecosystems. Sedimentological data...