Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of administered inorganic arsenic in most mammals. This study examined the disposition of pentavalent and trivalent dimethylated arsenic in mice after acute oral administration. Adult female mice were administered [14C]-DMA(V) (0.6 or 60 mg As/kg) and sacrificed serially over 24 h. Tissues and excreta were collected for analysis of radioactivity. Other mice were administered unlabeled DMA(V) (0.6 or 60 mg As/kg) or dimethylarsinous acid (DMA(III)) (0.6 mg As/kg) and sacrificed at 2 or 24 h. Tissues (2 h) and urine (24 h) were collected and analyzed for arsenicals. Absorption, distribution and excretion of [14C]-DMA(V) were rapid, as radioactivity was ...
Recent advances in our knowledge of arsenic carcinogenesis include the development of rat or mouse m...
[[abstract]]Parenteral administration of arsenic trioxide has recently been recognized as an effecti...
Arsenic methyltransferase (As3mt) catalyzes the conversion of inorganic arsenic (iAs) to its methyla...
Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of admini...
Exposure to monomethylarsonic acid (MMA(V)) and monomethylarsonous acid (MMA(III)) can result from t...
THE METABOLISM OF DIMETHYLARSINIC ACID (DMA) A COMMON PESTICIDE AND THE MAIN METABOLITE ...
Chronic exposure to inorganic arsenic (iAs) is carcinogenic to the human urinary bladder. It produce...
Less information is available on the metabolism of organic arsenicals compared to inorganic arsenic ...
Chronic ingestion of water containing inorganic arsenic (iAs) has been linked to a variety of advers...
Dimethylarsinic acid (DMA) has been used as an herbicide (cacodylic acid) and is the major metabolit...
The relationship of exposure dose and tissue concentration of parent chemical and metabolites is a c...
Monomethylarsonic acid (MMAV) and dimethylarsinic acid (DMAV) are active ingredients in pesticidal p...
AbstractArsenic is a proven human carcinogen. Although the mechanism of its carcinogenicity is still...
application/pdfPrevious studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) a...
Parenteral administration of arsenic trioxide has recently been recognized as an effective antineopl...
Recent advances in our knowledge of arsenic carcinogenesis include the development of rat or mouse m...
[[abstract]]Parenteral administration of arsenic trioxide has recently been recognized as an effecti...
Arsenic methyltransferase (As3mt) catalyzes the conversion of inorganic arsenic (iAs) to its methyla...
Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of admini...
Exposure to monomethylarsonic acid (MMA(V)) and monomethylarsonous acid (MMA(III)) can result from t...
THE METABOLISM OF DIMETHYLARSINIC ACID (DMA) A COMMON PESTICIDE AND THE MAIN METABOLITE ...
Chronic exposure to inorganic arsenic (iAs) is carcinogenic to the human urinary bladder. It produce...
Less information is available on the metabolism of organic arsenicals compared to inorganic arsenic ...
Chronic ingestion of water containing inorganic arsenic (iAs) has been linked to a variety of advers...
Dimethylarsinic acid (DMA) has been used as an herbicide (cacodylic acid) and is the major metabolit...
The relationship of exposure dose and tissue concentration of parent chemical and metabolites is a c...
Monomethylarsonic acid (MMAV) and dimethylarsinic acid (DMAV) are active ingredients in pesticidal p...
AbstractArsenic is a proven human carcinogen. Although the mechanism of its carcinogenicity is still...
application/pdfPrevious studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) a...
Parenteral administration of arsenic trioxide has recently been recognized as an effective antineopl...
Recent advances in our knowledge of arsenic carcinogenesis include the development of rat or mouse m...
[[abstract]]Parenteral administration of arsenic trioxide has recently been recognized as an effecti...
Arsenic methyltransferase (As3mt) catalyzes the conversion of inorganic arsenic (iAs) to its methyla...