THE METABOLISM OF DIMETHYLARSINIC ACID (DMA) A COMMON PESTICIDE AND THE MAIN METABOLITE OF INORGANIC ARSENIC IN MAMMALS, HAS BEEN STUDIED IN MICE, HAMSTERS AND MAN. MICE AND HAMSTERS WERE ADMINISTERED A SINGLE DOSE OF 74AS-DMA (40 MG AS/KG BODY WEIGHT) ORALLY, WHILE A HUMAN SUBJECT INGESTED DMA CORRESPONDING TO 0.1 MG AS/KG BODY WEIGHT. ION EXCHANGE CHROMATOGRAPHY, PAPER ELECTROPHORESIS, THIN LAYER CHROMA- TOGRAPHY AS WELL AS ARSINE GENERATION - GAS CHROMATOGRAPHY COMBINED WITH ATOMIC ABSORPTION SPECTROPHOTOMETRY OR MASS SPECTROMETRY WERE USED TO CHARACTERIZE THE ARSENIC METABOLITES IN URINE AND FECES COLLECTED OVER 48 HOURS AFTER ...
application/pdfPrevious studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) a...
Arsenic (13 oxidation state) methyltransferase (As3mt) cata-lyzes methylation of inorganic arsenic (...
The following arsenite methyltransferase activities (U/mg) were measured in untreated mice: liver, 1...
Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of admini...
Less information is available on the metabolism of organic arsenicals compared to inorganic arsenic ...
Dimethylarsinic acid (DMA) has been used as an herbicide (cacodylic acid) and is the major metabolit...
The toxicity of inorganic trivalent arsenic for living organisms is reduced by in vivo methylation o...
Monomethylarsonic acid (MMAV) and dimethylarsinic acid (DMAV) are active ingredients in pesticidal p...
Recent advances in our knowledge of arsenic carcinogenesis include the development of rat or mouse m...
Chronic exposure to inorganic arsenic (iAs) is carcinogenic to the human urinary bladder. It produce...
Arsenic toxicity is species-dependent for mammals and is transformed to other metabolites in various...
Arsenic is a proven human carcinogen. Although the mechanism of its carcinogenicity is still largely...
Exposure to monomethylarsonic acid (MMA(V)) and monomethylarsonous acid (MMA(III)) can result from t...
Despite of its known toxicity and potential to cause cancer, arsenic has been proven to be a very im...
The relationship of exposure dose and tissue concentration of parent chemical and metabolites is a c...
application/pdfPrevious studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) a...
Arsenic (13 oxidation state) methyltransferase (As3mt) cata-lyzes methylation of inorganic arsenic (...
The following arsenite methyltransferase activities (U/mg) were measured in untreated mice: liver, 1...
Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of admini...
Less information is available on the metabolism of organic arsenicals compared to inorganic arsenic ...
Dimethylarsinic acid (DMA) has been used as an herbicide (cacodylic acid) and is the major metabolit...
The toxicity of inorganic trivalent arsenic for living organisms is reduced by in vivo methylation o...
Monomethylarsonic acid (MMAV) and dimethylarsinic acid (DMAV) are active ingredients in pesticidal p...
Recent advances in our knowledge of arsenic carcinogenesis include the development of rat or mouse m...
Chronic exposure to inorganic arsenic (iAs) is carcinogenic to the human urinary bladder. It produce...
Arsenic toxicity is species-dependent for mammals and is transformed to other metabolites in various...
Arsenic is a proven human carcinogen. Although the mechanism of its carcinogenicity is still largely...
Exposure to monomethylarsonic acid (MMA(V)) and monomethylarsonous acid (MMA(III)) can result from t...
Despite of its known toxicity and potential to cause cancer, arsenic has been proven to be a very im...
The relationship of exposure dose and tissue concentration of parent chemical and metabolites is a c...
application/pdfPrevious studies have shown that DMSA (meso-2, 3-dimercaptosuccinic acid, succimer) a...
Arsenic (13 oxidation state) methyltransferase (As3mt) cata-lyzes methylation of inorganic arsenic (...
The following arsenite methyltransferase activities (U/mg) were measured in untreated mice: liver, 1...