Associations of T cell activation and inflammatory biomarkers with virological response to darunavir/ritonavir plus raltegravir therapy
- Taiwo, B.
- Matining, R. M.
- Zheng, L.
- Lederman, M. M.
- Rinaldo, C. R.
- Kim, P. S.
- Berzins, B. I.
- Kuritzkes, D. R.
- Jennings, A.
- Eron, J. J.
- Wilson, C. C.
Publication date
January 2013
DOIAbstract
One of the goals of antiretroviral therapy (ART) is to attenuate HIV-induced systemic immune activation and inflammation. We determined the dynamics of biomarkers of immune activation, microbial translocation and inflammation during initial ART with a nucleos(t)ide-sparing regimen of darunavir/ritonavir plus raltegravir. We also evaluated associations between these biomarkers and the virological response to the regimen
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