International audienceA pepsin resistance test performed at pH 1.2 and with high pepsin to protein ratio is one of the steps of the weight-of-evidence approach used for assessment of allergenicity of new proteins. However, the use of other in vitro digestibility tests, performed in more physiologically relevant conditions and in combination with immunological assays so as to increase the value of the information gained from the studies of stability of a novel protein to digestion for the overall allergenicity assessment, has been proposed. This study then aimed to investigate the stability to digestion of Cry1Ab protoxin and toxin, insecticidal proteins expressed in genetically modified crops, using simulated gastric fluid (SGF) at differen...
AbstractThe introduction of novel proteins to food products carries with it the need to assess the p...
The weight-of-evidence, case-by-case approach is considered the most appropriate way of assessing th...
Not AvailableBackground Development of chimeric Cry toxins by protein engineering of known and vali...
International audienceA pepsin resistance test performed at pH 1.2 and with high pepsin to protein r...
Rationale. Evaluation of the potential allergenicity of proteins derived from genetically modified f...
Abstract Background Susceptibility to pepsin digestion of candidate transgene products is regarded a...
Background: Susceptibility to pepsin digestion of candidate transgene products is regarded an import...
Background: Susceptibility to pepsin digestion of candidate transgene products is regarded an import...
IntroductionEvaluating the gastrointestinal fate of proteins is paramount to assess whether they are...
The susceptibility of newly expressed proteins to digestion by gastrointestinal proteases (e.g., pep...
This statement supplements and updates the GMO Panel guidance document on allergenicity of genetical...
IntroductionThe resistance of proteins to digestion may play a role in determining their allergenic ...
The safety evaluation of genetically modified food crops includes testing for stability in pepsin di...
This statement supplements and updates the GMO Panel guidance document on allergenicity of genetical...
The primary objective of the assessment of novel proteins is to evaluate whether they are safe to co...
AbstractThe introduction of novel proteins to food products carries with it the need to assess the p...
The weight-of-evidence, case-by-case approach is considered the most appropriate way of assessing th...
Not AvailableBackground Development of chimeric Cry toxins by protein engineering of known and vali...
International audienceA pepsin resistance test performed at pH 1.2 and with high pepsin to protein r...
Rationale. Evaluation of the potential allergenicity of proteins derived from genetically modified f...
Abstract Background Susceptibility to pepsin digestion of candidate transgene products is regarded a...
Background: Susceptibility to pepsin digestion of candidate transgene products is regarded an import...
Background: Susceptibility to pepsin digestion of candidate transgene products is regarded an import...
IntroductionEvaluating the gastrointestinal fate of proteins is paramount to assess whether they are...
The susceptibility of newly expressed proteins to digestion by gastrointestinal proteases (e.g., pep...
This statement supplements and updates the GMO Panel guidance document on allergenicity of genetical...
IntroductionThe resistance of proteins to digestion may play a role in determining their allergenic ...
The safety evaluation of genetically modified food crops includes testing for stability in pepsin di...
This statement supplements and updates the GMO Panel guidance document on allergenicity of genetical...
The primary objective of the assessment of novel proteins is to evaluate whether they are safe to co...
AbstractThe introduction of novel proteins to food products carries with it the need to assess the p...
The weight-of-evidence, case-by-case approach is considered the most appropriate way of assessing th...
Not AvailableBackground Development of chimeric Cry toxins by protein engineering of known and vali...