Summary of mutations identified from sequenced clones taken from transfer 20 (bacterial generation ~150). Clones were sequenced on the illumina MiSeq platform and reads aligned using BWA. Small variants (SNPs and small indels) were identified using GATK HaplotypeCaller and SNPeff and structural rearrangements identified using BreakDancer. Data are shown in figure 1, S1 and table S2
De novo mutations observed in individual IV.2. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.5. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.1. Sequenced reads were aligned to the hg19 reference hu...
<p>(A) In total, 117 mutational events (<a href="http://www.plosgenetics.org/article/info:doi/10.137...
SNPs and InDels between the isolates of the t331 lineage. The mutations were detected with the âBa...
<p>(A) A dynastic tree illustrating the relationship between mother, daughter, and granddaughter clo...
<p>Summary of all mutations (single nucleotide mutations (SNPs) and indels) identified in clones der...
<p>Identified mutations in clones isolated from populations 1.1 to 1.14 (evolved <i>in vivo</i> for ...
Excel file S2. List of de novo mutations in coding regions found in sequenced clones isolated from b...
Sequences of alleles identified by Sanger sequencing. The sequence of gRNA is shown in horizontal bl...
Code, logs and data for discovery and genotyping of SNPs and indels, in the the D.melanogaster genom...
The affordability of next generation sequencing (NGS) is transforming the field of mutation analysis...
<p>A) Correlation of numbers of SNPs and indels for the ORFs of <i>M</i>. <i>pneumoniae</i> genome. ...
<p>Plot of the microsatellite InDel variants per amplicon (m) detected by Illumina- (white bars), 45...
Impact of the four different mutation types that were agnostically identified through our holistic a...
De novo mutations observed in individual IV.2. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.5. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.1. Sequenced reads were aligned to the hg19 reference hu...
<p>(A) In total, 117 mutational events (<a href="http://www.plosgenetics.org/article/info:doi/10.137...
SNPs and InDels between the isolates of the t331 lineage. The mutations were detected with the âBa...
<p>(A) A dynastic tree illustrating the relationship between mother, daughter, and granddaughter clo...
<p>Summary of all mutations (single nucleotide mutations (SNPs) and indels) identified in clones der...
<p>Identified mutations in clones isolated from populations 1.1 to 1.14 (evolved <i>in vivo</i> for ...
Excel file S2. List of de novo mutations in coding regions found in sequenced clones isolated from b...
Sequences of alleles identified by Sanger sequencing. The sequence of gRNA is shown in horizontal bl...
Code, logs and data for discovery and genotyping of SNPs and indels, in the the D.melanogaster genom...
The affordability of next generation sequencing (NGS) is transforming the field of mutation analysis...
<p>A) Correlation of numbers of SNPs and indels for the ORFs of <i>M</i>. <i>pneumoniae</i> genome. ...
<p>Plot of the microsatellite InDel variants per amplicon (m) detected by Illumina- (white bars), 45...
Impact of the four different mutation types that were agnostically identified through our holistic a...
De novo mutations observed in individual IV.2. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.5. Sequenced reads were aligned to the hg19 reference hu...
De novo mutations observed in individual IV.1. Sequenced reads were aligned to the hg19 reference hu...