Sequences of alleles identified by Sanger sequencing. The sequence of gRNA is shown in horizontal black underlined region, the PAM site is the horizontal red underline. In 1A, 1B, 2A, 2B sequenced colonies mutations with 39bp deletion (dotted); 1C, 2C, 2D, 3B sequenced colonies wild-type alleles. In 3A sequenced colonies mutations with 9bp deletion (dotted).</p
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
<p>(A) HRM analysis plots and Sanger Sequencing chromatograms of serial dilutions of T790M <i>EGFR</...
<p>Sanger and NGS sequencing coverage of targeted CRISPR mutations at the <i>pfatp4</i> locus for AC...
In the T7EI assay note mutations in numbers 1 to 3. It’s possible to see 2 bands in the center of th...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
<p>Representative chromatograms (left) and pyrograms (right) of GNAS wild-type, GNAS R201C, and GNAS...
<p>The frequency estimated by Sanger sequencing is plotted for each substituted base for Line1 (uppe...
<p>All illustrated mutations were confirmed via sequencing the forward strand. Sample number and mut...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>(<i>A</i>) Example of an insertion mutation: IVS15-3-2insC in <i>COL6A2</i> identified byNGS (to ...
<p>Genomic sequence is shown at the top with the target sequences of a pair of TALEN colored in gree...
A) Locations of point mutations; B) presence of point mutations in the population at the indicated t...
<p>Wild type and deleted alleles are superimposed in SS electropherograms. In case #70, carrying a 2...
<p>All sequences generated by TILLING (see <a href="http://www.plosgenetics.org/article/info:doi/10....
<p>Candidate mutations in 9 autosomal dominant and 4 autosomal recessive NSHL families were shown in...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
<p>(A) HRM analysis plots and Sanger Sequencing chromatograms of serial dilutions of T790M <i>EGFR</...
<p>Sanger and NGS sequencing coverage of targeted CRISPR mutations at the <i>pfatp4</i> locus for AC...
In the T7EI assay note mutations in numbers 1 to 3. It’s possible to see 2 bands in the center of th...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
<p>Representative chromatograms (left) and pyrograms (right) of GNAS wild-type, GNAS R201C, and GNAS...
<p>The frequency estimated by Sanger sequencing is plotted for each substituted base for Line1 (uppe...
<p>All illustrated mutations were confirmed via sequencing the forward strand. Sample number and mut...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>(<i>A</i>) Example of an insertion mutation: IVS15-3-2insC in <i>COL6A2</i> identified byNGS (to ...
<p>Genomic sequence is shown at the top with the target sequences of a pair of TALEN colored in gree...
A) Locations of point mutations; B) presence of point mutations in the population at the indicated t...
<p>Wild type and deleted alleles are superimposed in SS electropherograms. In case #70, carrying a 2...
<p>All sequences generated by TILLING (see <a href="http://www.plosgenetics.org/article/info:doi/10....
<p>Candidate mutations in 9 autosomal dominant and 4 autosomal recessive NSHL families were shown in...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
<p>(A) HRM analysis plots and Sanger Sequencing chromatograms of serial dilutions of T790M <i>EGFR</...
<p>Sanger and NGS sequencing coverage of targeted CRISPR mutations at the <i>pfatp4</i> locus for AC...