Add to ORKGMost known heterocyclic amines (HCAs) are potent mutagens present at significant concentrations in cooked meats, and can be synthesized from burned mixtures of L-creatin(in)e with various amino acids. We hypothesize that novel mutagenic HCAs may be synthesized from a heated plant-based food simulating binary amino acid mixture: L-arginine and L-threonine. A two-part solid phase extraction is used to separate nitrogen heterocycles from byproducts followed by prep-HPLC to purify a small amount of a single compound, and characterization using GC-MS, IR, and NMR. The Ames mutagenicity assay using Salmonella TA98 is used to determine the mutagenic profile of the purified compound
Heterocyclic amines (HCAs) are carcinogenic molecules generated from the reaction of creatin(in)e an...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Most known heterocyclic amines (HCAs) are potent mutagens present at significant concentrations in c...
Most known heterocyclic amines (HCAs) are potent mutagens present at significant concentrations in c...
Investigation of cancer-inducing molecules in cooked foods has led to the discovery of mutagenic het...
It is well established in scientific literature that cooked meat and fish produce heterocyclic amine...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Previous research has demonstrated that creatinine and other amino acids in meat, when cooked at hig...
Heterocyclic Amines (HCAs) are a group of mutagenic and carcinogenic chemicals found in muscle meat ...
Investigation of cancer-inducing molecules in cooked foods has led to the discovery of mutagenic het...
Heterocyclic Amines (HCAs) are a group of mutagenic and caricinogenic chemicals found in muscle meat...
It is well established in scientific literature that cooked meat and fish produce carcinogenic heter...
It is well established in scientific literature that cooked meat and fish produce heterocyclic amine...
Various combinations of burned animal-based amino acids have been documented to show mutagenic chara...
Heterocyclic amines (HCAs) are carcinogenic molecules generated from the reaction of creatin(in)e an...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Most known heterocyclic amines (HCAs) are potent mutagens present at significant concentrations in c...
Most known heterocyclic amines (HCAs) are potent mutagens present at significant concentrations in c...
Investigation of cancer-inducing molecules in cooked foods has led to the discovery of mutagenic het...
It is well established in scientific literature that cooked meat and fish produce heterocyclic amine...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Previous research has demonstrated that creatinine and other amino acids in meat, when cooked at hig...
Heterocyclic Amines (HCAs) are a group of mutagenic and carcinogenic chemicals found in muscle meat ...
Investigation of cancer-inducing molecules in cooked foods has led to the discovery of mutagenic het...
Heterocyclic Amines (HCAs) are a group of mutagenic and caricinogenic chemicals found in muscle meat...
It is well established in scientific literature that cooked meat and fish produce carcinogenic heter...
It is well established in scientific literature that cooked meat and fish produce heterocyclic amine...
Various combinations of burned animal-based amino acids have been documented to show mutagenic chara...
Heterocyclic amines (HCAs) are carcinogenic molecules generated from the reaction of creatin(in)e an...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...
Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (H...