Add to ORKGIn the presence of TMSOTf and a trialkylamine base, acetic acid undergoes aldol addition to non-enolizable aldehydes under exceptionally mild conditions. Acidic workup yields the β-hydroxy carboxylic acid. The reaction appears to proceed via a three-step, one-pot process, including in situ trimethylsilyl ester formation, bis-silyl ketene acetal formation, and TMSOTf-catalyzed Mukaiyama aldol addition. Independently synthesized TMSOAc also undergoes aldol additions under similar conditions
In the presence of TMSOTf, a wide variety of terminal acetylenes add rapidly and efficiently to alde...
The Mukaiyama aldol reaction is a widely applied carbon–carbon bond forming reaction. However, despi...
In the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base, thioesters are r...
In the presence of TMSOTf and a trialkylamine base, acetic acid undergoes aldol addition to non-enol...
Various ketones, esters, amides, and thioesters add in high yield to dimethyl acetals in the presenc...
A slight excess of silyl trifluoromethanesulfonate mediates a tandem enol silane formation-Mukaiyama...
One-pot reactions were studied in order to develop procedures for the formation of important carbon-...
Abstract: A new aldol-type reaction has been developed that does not require the extremely basic con...
Aryl alkyl ketones, acetate esters, and acetamides undergo facile one-pot enol silane formation, Muk...
We described a one-pot vinylogous aldol addition of methyl 3-butenoate to aromatic aldehydes in the ...
(Trimethylsilyl) acetonitrile reacts smoothly with dimethyl acetals in the presence of stoichiometri...
Reactions that form a product with the same reactive functionality as that of one of the starting co...
In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and 2,6-lutidine, α,α-disubstit...
A single-pot three-component coupling reaction of silylglyoxylates (1), terminal alkynes, and aldehy...
A single-pot three-component coupling reaction of silylglyoxylates (1), terminal alkynes, and aldehy...
In the presence of TMSOTf, a wide variety of terminal acetylenes add rapidly and efficiently to alde...
The Mukaiyama aldol reaction is a widely applied carbon–carbon bond forming reaction. However, despi...
In the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base, thioesters are r...
In the presence of TMSOTf and a trialkylamine base, acetic acid undergoes aldol addition to non-enol...
Various ketones, esters, amides, and thioesters add in high yield to dimethyl acetals in the presenc...
A slight excess of silyl trifluoromethanesulfonate mediates a tandem enol silane formation-Mukaiyama...
One-pot reactions were studied in order to develop procedures for the formation of important carbon-...
Abstract: A new aldol-type reaction has been developed that does not require the extremely basic con...
Aryl alkyl ketones, acetate esters, and acetamides undergo facile one-pot enol silane formation, Muk...
We described a one-pot vinylogous aldol addition of methyl 3-butenoate to aromatic aldehydes in the ...
(Trimethylsilyl) acetonitrile reacts smoothly with dimethyl acetals in the presence of stoichiometri...
Reactions that form a product with the same reactive functionality as that of one of the starting co...
In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) and 2,6-lutidine, α,α-disubstit...
A single-pot three-component coupling reaction of silylglyoxylates (1), terminal alkynes, and aldehy...
A single-pot three-component coupling reaction of silylglyoxylates (1), terminal alkynes, and aldehy...
In the presence of TMSOTf, a wide variety of terminal acetylenes add rapidly and efficiently to alde...
The Mukaiyama aldol reaction is a widely applied carbon–carbon bond forming reaction. However, despi...
In the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base, thioesters are r...