Inroduction: For a long time there has been a belief among scientific investigators and medical men that certain diseases, both of man and animal were the direct result of a faulty diet. In other words, something which was needed by the body for maintenance of growth and health was thought to be frequently lacking in the diet of man and animal. Attention was first called to these accessory substances thru investigations into the cause of the disease beri-beri. In 1884, the Japanese Navy, under the direction of Admiral Takaki, positively demonstrated that beri-beri was the result of a faulty diet, but it was Eijkman who first produced the disease experimentally in birds. Hopkins first spoke of food accessories about 1908. He had tried to fe...