Significant over-represented KEGG pathways amongst overhaul treated samples.

Over-representation testing completed based on purple and black gene set clusters, as well as both clusters combined, identified from heatmap (Fig 2) using Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Twenty-two pathways had more significant genes than expected by chance in at least one of the three comparisons (raw p-value < 0.005). The color of the box represents the –log10(p-value) to give more significant values darker color while the actual p-values are printed inside each box; the grey box indicates no genes in the black cluster mapped to that pathway.