Effect of CNP-53 on the thickness of the hypertrophic and non-hypertrophic zones in the growth plate at the proximal end of the tibia.
- Keisho Hirota (4994384)
- Mayumi Furuya (2794603)
- Naomi Morozumi (4994399)
- Kazunori Yoshikiyo (5774975)
- Takafumi Yotsumoto (4994390)
- Toshimasa Jindo (4994387)
- Ryuichi Nakamura (4518085)
- Koichiro Murakami (5774978)
- Yohei Ueda (4994381)
- Takeshi Hanada (2727619)
- Hiroko Sade (5774981)
- Sayaka Yoshida (3406)
- Kei Enomoto (548372)
- Yugo Kanai (4994405)
- Ichiro Yamauchi (4112260)
- Takafumi Yamashita (5774984)
- Yoriko Ueda-Sakane (5774987)
- Toshihito Fujii (4994393)
- Akihiro Yasoda (4112263)
- Nobuya Inagaki (108987)
Publication date
September 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Representative example of the proximal end of the tibia stained with alcian blue/HE. The white and red arrows indicate the hypertrophic and non-hypertrophic zones, respectively. (B), (C) The average lengths of the hypertrophic (B) and non-hypertrophic (C) zones. The values are the means + SE. Open bars, vehicle (n = 5 in both genotypes); closed bars, CNP-53 (0.5 mg/kg/day, n = 6 in both genotypes). KO, CNP-KO rats; WT, WT rats. *, p p t-test.</p