Figure S2. Validation of mutation calling after filtering with Xenofilter and Xenome. A: IGV image of SNP rs2071313, located in the gene MEN1, of sample M041.X1 and M046.X1 after filtering with Xenome and XenofilteR. B: Validation of the SNP rs2071313 (MEN1) by Sanger sequencing with human-specific primers. (TIF 3324 kb
Sanger sequencing validation results of novel somatic EGFR mutation p.D587H (chr7:55233009G>C) in pa...
Table S1. List of congenic DEGs in the Sall2 KO line (MEFs). Congenic DEGs with missense mutations a...
Figure S5. Analysis of the Syt4 project. PCR amplification of the genomic region of interest with (a...
Figure S1. Performance of XenofilteR and Xenome on PDX samples. Mutation calling and read counts for...
Table S1. WGS of mouse strains mapped to human. Number of sequence reads from 3 mouse strains mapped...
Figure S3. Graphical abstract of Xenograft sequence analysis with XenofilteR. Sequence data obtained...
Table S2. Pathology estimate and SNVs of eight PDX samples. Percentage of mouse stromal cells, detec...
Table S3. Number of sequence reads after filtering of the in silico dataset. Number and percentages ...
Background: Mouse xenografts from (patient-derived) tumors (PDX) or tumor cell lines are widely used...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S4. Analysis of the Ikzf2 project. PCR amplification of the genomic region of interest from (...
a Validation of in vivo flank xenograft experiments using lentiviral ectopic over-expression of cand...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
The numbers of CTXs in each sample after filtering process and chromosome coordinates of all CTXs. 1...
Figure S6. Analysis of the Usp45 project. The figure shows the PCR amplification of the genomic regi...
Sanger sequencing validation results of novel somatic EGFR mutation p.D587H (chr7:55233009G>C) in pa...
Table S1. List of congenic DEGs in the Sall2 KO line (MEFs). Congenic DEGs with missense mutations a...
Figure S5. Analysis of the Syt4 project. PCR amplification of the genomic region of interest with (a...
Figure S1. Performance of XenofilteR and Xenome on PDX samples. Mutation calling and read counts for...
Table S1. WGS of mouse strains mapped to human. Number of sequence reads from 3 mouse strains mapped...
Figure S3. Graphical abstract of Xenograft sequence analysis with XenofilteR. Sequence data obtained...
Table S2. Pathology estimate and SNVs of eight PDX samples. Percentage of mouse stromal cells, detec...
Table S3. Number of sequence reads after filtering of the in silico dataset. Number and percentages ...
Background: Mouse xenografts from (patient-derived) tumors (PDX) or tumor cell lines are widely used...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S4. Analysis of the Ikzf2 project. PCR amplification of the genomic region of interest from (...
a Validation of in vivo flank xenograft experiments using lentiviral ectopic over-expression of cand...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
The numbers of CTXs in each sample after filtering process and chromosome coordinates of all CTXs. 1...
Figure S6. Analysis of the Usp45 project. The figure shows the PCR amplification of the genomic regi...
Sanger sequencing validation results of novel somatic EGFR mutation p.D587H (chr7:55233009G>C) in pa...
Table S1. List of congenic DEGs in the Sall2 KO line (MEFs). Congenic DEGs with missense mutations a...
Figure S5. Analysis of the Syt4 project. PCR amplification of the genomic region of interest with (a...