Table S1. List of congenic DEGs in the Sall2 KO line (MEFs). Congenic DEGs with missense mutations are depicted in red. Table S2. DEGs between Sall2 WT and KO MEFs under doxorubicin perturbation (FDRâ<â0.05). Ang, one of the most downregulated genes in the Sall2 KO line, is depicted in red. (XLSX 76 kb
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
Heat map of all mapped traits across the murine genome. The QTL heat map for all members of the clus...
Figure S3. A, B. Examples of mutagenized loxP sites identified upon TA cloning PCR products from lox...
Table S1. DEGs between Sall2 WT and Sall2 KO (FDRâ<â0.05). Ang, one of the most downregulated ge...
Table S1. Homozygous variants from a Sall2 +/â littermate used to crossvalidate the congenic footp...
Table S1-S5. KO-linked variants in Gtf2ird1, Mecp2, Stc1 and Itch knockout studies, including a Sall...
Pervasive downregulation of Ang in 129 mice. A) Left: IGV snapshot of Ang/Rnase4 gene expression acr...
Whole genome histogram of novel/existing variants in Gtf2ird1, Mecp2, Stc1, Itch, Sall2 and Hnrnpd/A...
Validation of the murine Sall2 gene deletion by CRISPR-Cas9. A) Representative Western blot for SALL...
Per strain over-represented pathways using genes containing private missense SNPs. For each strain s...
Table S1. Cochran-Armitage test for trend distribution in knockouts (p-values) Table S2. Casp4 varia...
Schematic view of the sources of genetic variation identified in KO/KI congenic mice. First, the cho...
Whole genome histogram of novel/existing variants in two WES studies. WES samples from the GEO datas...
Candidate genes identified in the RF/J analysis. All genes which contained at least one missense SNP...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
Heat map of all mapped traits across the murine genome. The QTL heat map for all members of the clus...
Figure S3. A, B. Examples of mutagenized loxP sites identified upon TA cloning PCR products from lox...
Table S1. DEGs between Sall2 WT and Sall2 KO (FDRâ<â0.05). Ang, one of the most downregulated ge...
Table S1. Homozygous variants from a Sall2 +/â littermate used to crossvalidate the congenic footp...
Table S1-S5. KO-linked variants in Gtf2ird1, Mecp2, Stc1 and Itch knockout studies, including a Sall...
Pervasive downregulation of Ang in 129 mice. A) Left: IGV snapshot of Ang/Rnase4 gene expression acr...
Whole genome histogram of novel/existing variants in Gtf2ird1, Mecp2, Stc1, Itch, Sall2 and Hnrnpd/A...
Validation of the murine Sall2 gene deletion by CRISPR-Cas9. A) Representative Western blot for SALL...
Per strain over-represented pathways using genes containing private missense SNPs. For each strain s...
Table S1. Cochran-Armitage test for trend distribution in knockouts (p-values) Table S2. Casp4 varia...
Schematic view of the sources of genetic variation identified in KO/KI congenic mice. First, the cho...
Whole genome histogram of novel/existing variants in two WES studies. WES samples from the GEO datas...
Candidate genes identified in the RF/J analysis. All genes which contained at least one missense SNP...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
Heat map of all mapped traits across the murine genome. The QTL heat map for all members of the clus...
Figure S3. A, B. Examples of mutagenized loxP sites identified upon TA cloning PCR products from lox...