Figure S3. Graphical abstract of Xenograft sequence analysis with XenofilteR. Sequence data obtained from xenograft samples contains sequence reads from mouse as well as sequence reads from human origin. XenofilteR separates these reads allowing further downstream analysis based on sequence reads of human origin only. (TIF 3293 kb
Table S6. Location, sequence, mismatch number, and primer sequences for off-target sites listed by g...
Background - Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that ...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
Table S1. WGS of mouse strains mapped to human. Number of sequence reads from 3 mouse strains mapped...
Table S3. Number of sequence reads after filtering of the in silico dataset. Number and percentages ...
Table S2. Pathology estimate and SNVs of eight PDX samples. Percentage of mouse stromal cells, detec...
Figure S2. Validation of mutation calling after filtering with Xenofilter and Xenome. A: IGV image o...
Figure S1. Performance of XenofilteR and Xenome on PDX samples. Mutation calling and read counts for...
Background: Mouse xenografts from (patient-derived) tumors (PDX) or tumor cell lines are widely used...
Pipeline of data processing. Figure S2. Comparison with other methods to separate human and mouse re...
The numbers of CTXs in each sample after filtering process and chromosome coordinates of all CTXs. 1...
Novel candidate conserved homologs associated with genes sets. Sheet 1: results using tissue gene se...
Mouse and human tumor metadata and differential expression results of RNA-seq data. Sample informati...
Table S5. Summary of SNVs, InDels, CNVs, and fusions of the 50 xenografts by targeted sequencing. (D...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Table S6. Location, sequence, mismatch number, and primer sequences for off-target sites listed by g...
Background - Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that ...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...
Table S1. WGS of mouse strains mapped to human. Number of sequence reads from 3 mouse strains mapped...
Table S3. Number of sequence reads after filtering of the in silico dataset. Number and percentages ...
Table S2. Pathology estimate and SNVs of eight PDX samples. Percentage of mouse stromal cells, detec...
Figure S2. Validation of mutation calling after filtering with Xenofilter and Xenome. A: IGV image o...
Figure S1. Performance of XenofilteR and Xenome on PDX samples. Mutation calling and read counts for...
Background: Mouse xenografts from (patient-derived) tumors (PDX) or tumor cell lines are widely used...
Pipeline of data processing. Figure S2. Comparison with other methods to separate human and mouse re...
The numbers of CTXs in each sample after filtering process and chromosome coordinates of all CTXs. 1...
Novel candidate conserved homologs associated with genes sets. Sheet 1: results using tissue gene se...
Mouse and human tumor metadata and differential expression results of RNA-seq data. Sample informati...
Table S5. Summary of SNVs, InDels, CNVs, and fusions of the 50 xenografts by targeted sequencing. (D...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Table S6. Location, sequence, mismatch number, and primer sequences for off-target sites listed by g...
Background - Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that ...
Figure S7. Analysis of the Rapgef5 project. PCR amplification of the genomic region of interest with...