REST can occupy across C19MC in a cell type-dependent manner and it is expression negatively correlates with CEBPB.

A, ENCODE ChIPSeq data (hg19) of 8 human cancer cell lines to show that REST can bind all across C19MC and surrounding genomic areas (left:combined map; right: individual cell line map). B, Schematic showing transcription regulatory factor binding map of full C19MC region. Also see S3 Fig for UCSC genome browser data. C, RNASeq expression data of C19MC binding factors in REST-based tumor groups. D, Correlation heatmap (left) and correlation co-efficiency (right) plots of full C19MC binding factors (RNASeq) to C19MC expression (miRNASeq) in primary TNBC-based miRNASeq matched dataset. E, Correlation heatmap (left) and correlation co-efficiency (right) plots of full C19MC binding factors (RNASeq) to C19MC expression (miRNASeq) in primary C19MC-based RNASeq matched dataset.