Additional file 4: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Additional file 7: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Polysome-bound and ribosome-free RNA-seq data of D0 vs. D15 comparison (FDR < 0.05). (XLSX 3849 kb

Additional file 4: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Ribosome-free RNA-seq data of comparisons of each sample against the preceding time-point (FDR < 0.0...

Table_4_Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy.XLSX

Konstantina Portokallidou (14604479)
Nikolas Dovrolis (6844682)
Georgia Ragia (14604482)
Natalia Atzemian (14604485)
George Kolios (1820380)
Vangelis G. Manolopoulos (14301476)

February 2023

IntroductionHeart failure (HF) is a complex clinical syndrome leading to high morbidity. In this stu...

Additional file 3: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S1. Empirical distribution of FDR values â¤0.05 for 1000 permutations. Histogram with the nu...

Additional file 8: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S2. Disease-specific DEGs clusters samples by phenotype in publicly available expression data...

Additional file 9: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S7. Predicted biofunctions. IPA biofunctions predicted to be increased or decreased for Analys...

Additional file 6: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S5. Enriched IPA Canonical Pathways. IPA canonical pathways for p ≤ 0.05 for Analysis 1 (HF-DE...

Additional file 1: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S1. Sample table. Characteristics including sex, race, ethnicity, age, cause of death (if appl...

Additional file 7: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S6. Enriched IPA Toxicity. IPA toxicity lists for p ≤ 0.05 for Analysis 1 (HF-DEGs). (XLSX 15 ...

Additional file 2: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S2. RNAseq quality control table. Raw read counts ranged from ~â36 to 66 million. Read count...

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary E. Sweet
Andrea Cocciolo
Dobromir Slavov
Kenneth L. Jones
Joseph R. Sweet
Sharon L. Graw
T. Brett Reece
Amrut V. Ambardekar
Michael R. Bristow
Luisa Mestroni
Matthew R. G. Taylor

November 2018

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ven...

Additional file 2: Figure S1. of Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Vinicius Tragante (113546)
Johannes Gho (4051384)
Janine Felix (3535616)
Ramachandran Vasan (705059)
Nicholas Smith (3160875)
Benjamin Voight (120870)
Colin Palmer (165015)
Pim van der Harst (65060)
Jason Moore (377082)
Folkert Asselbergs (3246126)

May 2017

Overlapping genes among significant pathways for hearf failure before data processing. (PDF 145Â kb

Additional file 3: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Polysome-bound RNA-seq data of comparisons of each sample against the preceding time-point (FDR < 0....

Identification of a Common Gene Expression Signature in Dilated Cardiomyopathy Across Independent Microarray Studies

Barth, Andreas S.
Kuner, Ruprecht
Buness, Andreas
Ruschhaupt, Markus
Merk, Sylvia
Zwermann, Ludwig
Kääb, Stefan
Kreuzer, Eckart
Steinbeck, Gerhard
Mansmann, Ulrich
Poustka, Annemarie
Nabauer, Michael
Sültmann, Holger

October 2006

ObjectivesThis study was designed to identify a common gene expression signature in dilated cardiomy...

Additional file 4: of Genetics of heart rate in heart failure patients (GenHRate)

Kaleigh Evans (6723020)
Heidi Wirtz (3469394)
Jia Li (160557)
Ruicong She (6723023)
Juan Maya (6723026)
Hongsheng Gui (181101)
Andrew Hamer (6723029)
Christophe Depre (2217061)
David Lanfear (6723032)

May 2019

Figure S3. Manhattan Plot of the gene-wise analysis of heart rate. Blue reference line: 1x10-5, Red ...

Additional file 7: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Polysome-bound and ribosome-free RNA-seq data of D0 vs. D15 comparison (FDR < 0.05). (XLSX 3849 kb

Additional file 4: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Ribosome-free RNA-seq data of comparisons of each sample against the preceding time-point (FDR < 0.0...

Table_4_Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy.XLSX

Konstantina Portokallidou (14604479)
Nikolas Dovrolis (6844682)
Georgia Ragia (14604482)
Natalia Atzemian (14604485)
George Kolios (1820380)
Vangelis G. Manolopoulos (14301476)

February 2023

IntroductionHeart failure (HF) is a complex clinical syndrome leading to high morbidity. In this stu...

Additional file 3: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S1. Empirical distribution of FDR values â¤0.05 for 1000 permutations. Histogram with the nu...

Additional file 8: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S2. Disease-specific DEGs clusters samples by phenotype in publicly available expression data...

Additional file 9: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S7. Predicted biofunctions. IPA biofunctions predicted to be increased or decreased for Analys...

Additional file 6: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S5. Enriched IPA Canonical Pathways. IPA canonical pathways for p ≤ 0.05 for Analysis 1 (HF-DE...

Additional file 1: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S1. Sample table. Characteristics including sex, race, ethnicity, age, cause of death (if appl...

Additional file 7: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S6. Enriched IPA Toxicity. IPA toxicity lists for p ≤ 0.05 for Analysis 1 (HF-DEGs). (XLSX 15 ...

Additional file 2: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S2. RNAseq quality control table. Raw read counts ranged from ~â36 to 66 million. Read count...

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary E. Sweet
Andrea Cocciolo
Dobromir Slavov
Kenneth L. Jones
Joseph R. Sweet
Sharon L. Graw
T. Brett Reece
Amrut V. Ambardekar
Michael R. Bristow
Luisa Mestroni
Matthew R. G. Taylor

November 2018

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ven...

Additional file 2: Figure S1. of Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Vinicius Tragante (113546)
Johannes Gho (4051384)
Janine Felix (3535616)
Ramachandran Vasan (705059)
Nicholas Smith (3160875)
Benjamin Voight (120870)
Colin Palmer (165015)
Pim van der Harst (65060)
Jason Moore (377082)
Folkert Asselbergs (3246126)

May 2017

Overlapping genes among significant pathways for hearf failure before data processing. (PDF 145Â kb

Additional file 3: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Polysome-bound RNA-seq data of comparisons of each sample against the preceding time-point (FDR < 0....

Identification of a Common Gene Expression Signature in Dilated Cardiomyopathy Across Independent Microarray Studies

Barth, Andreas S.
Kuner, Ruprecht
Buness, Andreas
Ruschhaupt, Markus
Merk, Sylvia
Zwermann, Ludwig
Kääb, Stefan
Kreuzer, Eckart
Steinbeck, Gerhard
Mansmann, Ulrich
Poustka, Annemarie
Nabauer, Michael
Sültmann, Holger

October 2006

ObjectivesThis study was designed to identify a common gene expression signature in dilated cardiomy...

Additional file 4: of Genetics of heart rate in heart failure patients (GenHRate)

Kaleigh Evans (6723020)
Heidi Wirtz (3469394)
Jia Li (160557)
Ruicong She (6723023)
Juan Maya (6723026)
Hongsheng Gui (181101)
Andrew Hamer (6723029)
Christophe Depre (2217061)
David Lanfear (6723032)

May 2019

Figure S3. Manhattan Plot of the gene-wise analysis of heart rate. Blue reference line: 1x10-5, Red ...

Additional file 7: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Polysome-bound and ribosome-free RNA-seq data of D0 vs. D15 comparison (FDR < 0.05). (XLSX 3849 kb

Additional file 4: of Cardiomyogenic differentiation is fine-tuned by differential mRNA association with polysomes

Isabela Pereira (4418380)
Lucia Spangenberg (3319449)
Anny Robert (5679008)
Rocío Amorín (6028229)
Marco Stimamiglio (6472004)
Hugo Naya (144710)
Bruno Dallagiovanna (470734)

March 2019

Ribosome-free RNA-seq data of comparisons of each sample against the preceding time-point (FDR < 0.0...

Table_4_Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy.XLSX

Konstantina Portokallidou (14604479)
Nikolas Dovrolis (6844682)
Georgia Ragia (14604482)
Natalia Atzemian (14604485)
George Kolios (1820380)
Vangelis G. Manolopoulos (14301476)

February 2023

IntroductionHeart failure (HF) is a complex clinical syndrome leading to high morbidity. In this stu...

Additional file 4: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Abstract

Extracted data

Additional file 4: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Abstract

Extracted data

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