Additional file 7: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Table1_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table6_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary E. Sweet
Andrea Cocciolo
Dobromir Slavov
Kenneth L. Jones
Joseph R. Sweet
Sharon L. Graw
T. Brett Reece
Amrut V. Ambardekar
Michael R. Bristow
Luisa Mestroni
Matthew R. G. Taylor

November 2018

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ven...

Additional file 6: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S5. Enriched IPA Canonical Pathways. IPA canonical pathways for p ≤ 0.05 for Analysis 1 (HF-DE...

Additional file 9: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S7. Predicted biofunctions. IPA biofunctions predicted to be increased or decreased for Analys...

Additional file 4: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S3. DEGs for unadjusted gene expression. DEGs at FDR ≤ 0.05 in DCM vs NF and ICM vs NF. (XLSX ...

Additional file 1: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S1. Sample table. Characteristics including sex, race, ethnicity, age, cause of death (if appl...

Additional file 8: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S2. Disease-specific DEGs clusters samples by phenotype in publicly available expression data...

Additional file 3: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S1. Empirical distribution of FDR values â¤0.05 for 1000 permutations. Histogram with the nu...

Additional file 2: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S2. RNAseq quality control table. Raw read counts ranged from ~â36 to 66 million. Read count...

Additional file 2: Figure S1. of Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Vinicius Tragante (113546)
Johannes Gho (4051384)
Janine Felix (3535616)
Ramachandran Vasan (705059)
Nicholas Smith (3160875)
Benjamin Voight (120870)
Colin Palmer (165015)
Pim van der Harst (65060)
Jason Moore (377082)
Folkert Asselbergs (3246126)

May 2017

Overlapping genes among significant pathways for hearf failure before data processing. (PDF 145Â kb

Table8_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.docx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table_1_Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy.DOCX

Konstantina Portokallidou (14604479)
Nikolas Dovrolis (6844682)
Georgia Ragia (14604482)
Natalia Atzemian (14604485)
George Kolios (1820380)
Vangelis G. Manolopoulos (14301476)

February 2023

IntroductionHeart failure (HF) is a complex clinical syndrome leading to high morbidity. In this stu...

Additional file 7: of In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer

Basel Abu-Jamous (281243)
Francesca Buffa (132341)
Adrian Harris (94740)
Asoke Nandi (3577592)

June 2017

These Tables show the transcript factor analysis of the various clusters, sub-clusters, and hypoxia ...

Table7_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table1_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table6_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary E. Sweet
Andrea Cocciolo
Dobromir Slavov
Kenneth L. Jones
Joseph R. Sweet
Sharon L. Graw
T. Brett Reece
Amrut V. Ambardekar
Michael R. Bristow
Luisa Mestroni
Matthew R. G. Taylor

November 2018

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ven...

Additional file 6: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S5. Enriched IPA Canonical Pathways. IPA canonical pathways for p ≤ 0.05 for Analysis 1 (HF-DE...

Additional file 9: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S7. Predicted biofunctions. IPA biofunctions predicted to be increased or decreased for Analys...

Additional file 4: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S3. DEGs for unadjusted gene expression. DEGs at FDR ≤ 0.05 in DCM vs NF and ICM vs NF. (XLSX ...

Additional file 1: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S1. Sample table. Characteristics including sex, race, ethnicity, age, cause of death (if appl...

Additional file 8: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S2. Disease-specific DEGs clusters samples by phenotype in publicly available expression data...

Additional file 3: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Figure S1. Empirical distribution of FDR values â¤0.05 for 1000 permutations. Histogram with the nu...

Additional file 2: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary Sweet (5957306)
Andrea Cocciolo (5957309)
Dobromir Slavov (477830)
Kenneth Jones (781854)
Joseph Sweet (5957312)
Sharon Graw (5957315)
T. Reece (5957318)
Amrut Ambardekar (5957321)
Michael Bristow (5957324)
Luisa Mestroni (477836)
Matthew Taylor (39753)

November 2018

Table S2. RNAseq quality control table. Raw read counts ranged from ~â36 to 66 million. Read count...

Additional file 2: Figure S1. of Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

Vinicius Tragante (113546)
Johannes Gho (4051384)
Janine Felix (3535616)
Ramachandran Vasan (705059)
Nicholas Smith (3160875)
Benjamin Voight (120870)
Colin Palmer (165015)
Pim van der Harst (65060)
Jason Moore (377082)
Folkert Asselbergs (3246126)

May 2017

Overlapping genes among significant pathways for hearf failure before data processing. (PDF 145Â kb

Table8_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.docx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table_1_Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy.DOCX

Konstantina Portokallidou (14604479)
Nikolas Dovrolis (6844682)
Georgia Ragia (14604482)
Natalia Atzemian (14604485)
George Kolios (1820380)
Vangelis G. Manolopoulos (14301476)

February 2023

IntroductionHeart failure (HF) is a complex clinical syndrome leading to high morbidity. In this stu...

Additional file 7: of In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer

Basel Abu-Jamous (281243)
Francesca Buffa (132341)
Adrian Harris (94740)
Asoke Nandi (3577592)

June 2017

These Tables show the transcript factor analysis of the various clusters, sub-clusters, and hypoxia ...

Table7_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table1_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Table6_ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling.xlsx

Sumra Komal (11152758)
Atia Gohar (16712961)
Saad Althobaiti (16712964)
Ishtiaq Ahmad Khan (4840206)
Liu-Gen Cui (16712967)
Li-Rong Zhang (2399257)
Sheng-Na Han (11152764)
Muhammad Shakeel (509491)

July 2023

Heart Failure (HF) is a complex clinical syndrome in which the heart is unable to provide enough blo...

Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Mary E. Sweet
Andrea Cocciolo
Dobromir Slavov
Kenneth L. Jones
Joseph R. Sweet
Sharon L. Graw
T. Brett Reece
Amrut V. Ambardekar
Michael R. Bristow
Luisa Mestroni
Matthew R. G. Taylor

November 2018

Abstract Background Current heart failure (HF) treatment is based on targeting symptoms and left ven...

Additional file 7: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Abstract

Extracted data

Additional file 7: of Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure

Abstract

Extracted data

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